- Sympathetic Regulation of Aquaporin Water Channels in Rat Kidney
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Lee J, Yoo K, Oh Y, Lim DY
- KMID: 2071594
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):181-185.
Whether there exists a sympathetic neural regulation on the aquaporin (AQP) channels in the kidney was examined. Male Sprague-Dawley rats were used. They were renal nerve denervated by stripping the... -
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- Intrinsic Gating in Inward Rectifier Potassium Channels (Kir2.1) with Low Polyamine Affinity Generated by Site Directed Mutagenesis
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So I, Ashmole I, Soh H, Park C, Spencer P, Leyland M, Stanfield
- KMID: 2071587
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):131-142.
We have studied mutant forms of Kir2.1 in which an aspartate residue (D172), important for gating by intracellular polyamines, is replaced by one of three basic residues (Arg, Lys or... -
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- Neurotrophic and Neuritogenic Effects of Water Extracts of Rhizoma of Coptis chinensis Franch in PC12 Cells
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Kwon GY, Choe BK, Kim SK
- KMID: 2071593
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):175-179.
Coptis chinensis (CC) is one of the traditional herbs used in Oriental medicine for the treatment of gastrointestinal disorders, anxiety, and insomnia. In this study, neurotrophic and neuritogenic effects of... -
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- Effects of Chlorhexidine Digluconate on Rotational Rate of n- (9-Anthroyloxy) stearic Acid in Porphyromonas ginginvalis Outer Membranes
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Jang HO, Cha SK, Lee C, Choi MG, Huh SR, Shin SH, Chung IK, Yun I
- KMID: 2071586
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):125-130.
The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n- (9-anthroyloxy) stearic acid was used... -
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- Effects of Local Anesthetics on Rotational Mobility of n- (9-Anthroyloxy) stearic Acid in Neuronal Membranes
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Jang HO, Lee C, Choi MG, Shin SH, Chung IK, Yun I
- KMID: 2071585
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):119-124.
To elucidate the molecular mechanism of pharmacological action of local anesthetics, we studied membrane actions of tetracaine, bupivacaine, lidocaine, prilocaine and procaine. Fluorescence polarization of n- (9-anthroyloxy) stearic acid (n-AS)... -
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- Effects of Dopamine on Intracellular pH in Opossum Kidney Cells
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Kang KW, Kim YK
- KMID: 2071595
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):187-191.
Na+/H+ exchanger (NHE) has a critical role in regulation of intracellular pH (pHi) in the renal proximal tubular cells. It has recently been shown that dopamine inhibits NHE in the... -
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- Consistent and Specific Suppression of Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells by Poly-L-Lysine
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Lee CJ, Lee JH, Seok JH, Hur GM, Park JS, Bae S, Jang HS, Park SC
- KMID: 2071588
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):143-147.
Poly-L-lysine (PLL) was reported to suppress mucin release from airway goblet cells during 30 min treatment period. In this study, we investigated whether PLL consistently suppresses mucin release from cultured... -
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- Effects of gamma-Aminobutyric Acid on Intrinsic Cholinergic Action in Exocrine Secretion of Isolated, Perfused Rat Pancreas
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Park YD, Park HS, Cui ZY, Park HJ
- KMID: 2071592
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):169-174.
gamma-Aminobutyric acid (GABA) has been reported to enhance exocrine secretion evoked not only by secretagogues but also by intrinsic neuronal excitation in the pancreas. The pancreas contains cholinergic neurons abundantly... -
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- Alteration of Substrate Specificity by Common Variants, E158K/E308G and V257M, in Human Hepatic Drug-metabolizing Enzyme, Flavin-containing Monooxygenase 3
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Lee JK, Kang JH, Cha YN, Chung WG, Park CS
- KMID: 2071590
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):157-162.
Our earlier studies found a significant correlation between the activities of ranitidine N-oxidation catalyzed by hepatic flavin-containing monooxygenase (FMO) and the presence of mutations in exon 4 (E158K) and exon... -
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- Comparison of Vasodilator Effects of Platycodin D and D3 in Rats
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Lim DY, Kim BC, Lee EB
- KMID: 2071589
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):149-155.
The aim of the present study was to examine the effects of platycodin D and D3, which are active components derived from the roots of Platycodon grandiflorum A. DC., on... -
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- Transduction of Tat-Superoxide Dismutase into Insulin-producing MIN6N Cells Reduces Streptozotocin-induced Cytotoxicity
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Choung IS, Eum WS, Li MZ, Sin GS, Kang JH, Park J, Choi SY, Kwon HY
- KMID: 2071591
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):163-168.
The reactive oxygen species (ROS) are considered to be an important mediator in pancreatic beta cell destruction, thereby triggering the development of insulin-dependent diabetes mellitus. In the present study, HIV-1... -
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