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Enhanced Expression of Aldosterone Synthase and Adrenomedullin in Left and Right Ventricular Hypertrophy in Rats

Lee JU, Lee S, Kim S, Lee WJ

  • KMID: 1615003
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):121-126.
The pathophysiological implications of aldosterone and adrenomedullin in the cardiac ventricular hypertrophy were examined. Male Sprague-Dawley rats were treated with deoxycorticosterone acetate (DOCA)-salt and monocrotaline (MCT) to selectively elicit left...
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Noradrenergic Modulation of Spontaneous Inhibitory Postsynaptic Currents in the Hypothalamic Paraventricular Nucleus

Lee LH, Chong W, Lee K, Park JB, Ryu PD

  • KMID: 1614992
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):71-80.
Previous studies have suggested that brain stem noradrenergic inputs differentially modulate neurons in the paraventricular nucleus (PVN). Here, we compared the effects of norepinephrine (NE) on spontaneous GABAergic inhibitory postsynaptic...
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Increase of Intracellular Ca2+ Concentration Induced by Lysophosphatidylcholine in Murine Aortic Endothelial Cells

Zhu MH, Park SJ, Kim HJ, Yang DK, Suh SH, So I, Kim KW

  • KMID: 1614997
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):93-100.
Effects of oxidized low-density lipoprotein (ox-LDL), l-alpha-stearoyl-lysophosphatidylcholine (LPC), on intracellular Ca2+ concentration were examined in mouse endothelial cells by measuring intracellular Ca2+ concentration ([Ca2+]i) with fura 2-AM and reverse transcription-polymerase...
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Effect of Ca2+-channel Blockers on Norepinephrine Release in the Rat Hippocampal Slice and Synaptosome

Kim SW, Jung KY, Choi BK

  • KMID: 1614995
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):87-92.
The aim of this study was to investigate the role of Ca2+-channel blockers in norepinephrine (NE) release from rat hippocampus. Slices and synaptosomes were incubated with [3H]-NE and the releases...
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Changes in the Expressional Levels of Sarcoplasmic Reticulum Ca2+-regulatory Proteins in the Postnatal Developing Rat Heart

Lee EH, Park SS, Lee JS, Seo YJ, Kim YH, Kim HW

  • KMID: 1614999
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):101-108.
In the present study, the postnatal developmental changes in the expressional levels of cardiac sarcoplasmic reticulum (SR) Ca2+ regulatory proteins, i.e. Ca2+-ATPase, phospholamban, and Ca2+ release channel, were investigated. Both...
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Muscarine M2 Receptor-mediated Presynaptic Inhibition of GABAergic Transmission in Rat Meynert Neurons

Jang IS, Akaike N

  • KMID: 1614991
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):63-70.
Cholinergic modulation of GABAergic spontaneous miniature inhibitory postsynaptic currents (mIPSCs) by the activation of muscarine receptors was investigated in mechanically dissociated rat nucleus basalis of the Meynert neurons using the...
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Increases in Effective Cleft Glutamate Concentration During Expression of LTP

Jung SH, Choi S

  • KMID: 1615001
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):113-120.
Long-term potentiation (LTP) at hippocampal CA3-CA1 synapses is often associated with increases in quantal size, traditionally attributed to enhanced availability or efficacy of postsynaptic glutamate receptors. However, augmented quantal size...
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The Regulation of AP-1 DNA Binding Activity by Long-term Nicotine Stimulation in Bovine Adrenal Medullary Chromaffin Cells: Role of Second Messengers

Lee JK, Choi SS, Suh HW

  • KMID: 1615000
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):109-112.
The signal pathways involved in the regulation of AP-1 DNA binding activity in long-term nicotine stimulated bovine adrenal medullary chromaffin (BAMC) cells have not been well characterized. To understand the...
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Correlation between mEPSC Amplitude and Rise Time upon the Blockade of AMPA Receptor Desensitization at Hippocampal Synapses

Jung SH, Choi S

  • KMID: 1614994
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):81-86.
Conventional views of synaptic transmission generally overlook the possibility of "postfusional- control" the regulation of the speed or completeness of transmitter release upon vesicular fusion. However, such regulation often occurs...
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Upregulation of Renal Renin-Angiotensin System in Rats with Adriamycin-Induced Nephrosis

Kim SW, Lee JU, Han SW, Ryu JH, Oh YW, Kim NH, Choi KC, Kim HJ

  • KMID: 1615005
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):127-130.
The present study was aimed to investigate whether the adriamycin-induced nephrosis is associated with an altered regulation of local renin-angiotensin system (RAS) in the kidney. Rats were subjected to a...
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