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A RhD Negative Patient Failed to Produce Detectable Anti-D after Transfusion of 35 Units of RhD Positive Red Blood Cells

Lee WM, Kim JH, Ha JS, Ryoo NH, Jeon DS, Kim JR, Cho D

In the present day, pretransfusion tests include ABO and RhD grouping, antibody screening, antibody identification, and cross matching. Although error rates for these tests have decreased compared to those in...
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Comparison Study with Enzyme Immunoassay and Chemiluminescence Immunoassay for Hepatitis B Virus Surface Antigen Detection

Huh HJ, Chae SL, Cha YJ

BACKGROUND: The serological detection of the surface antigen (HBsAg) of hepatitis B virus (HBV) is the basis of detection of HBV infections in blood donors and patients with hepatitis....
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Seven Cases of Decreased Serum Valproic Acid Concentration During Concomitant Use of Carbapenem Antibiotics

Lee SG, Kim JH, Joo JY, Kwon OH

Valproic acid (VPA) is a commonly prescribed anticonvulsant drug for the treatment of various forms of epilepsy. Concomitant administration of VPA and carbapenem antibiotics such as panipenem/ betamipron and meropenem...
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Characteristics of Acute Myeloid Leukemia without HLA-DR Expression

Moon H, Lee S, Huh J, Chung WS

BACKGROUND: HLA-DR negativity is known to be useful for distinguishing acute promyelocytic leukemia (APL) from other subtypes of AML, but non-APL cases without HLA-DR antigen expression have been reported....
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Evaluation of Viva-E Drug Testing System

Chung HS, Lee ST, Lee SY

BACKGROUND: The importance and usefulness of therapeutic drug monitoring (TDM) have been emphasized, and analysis of drugs has been increased in clinical laboratories. We evaluated the analytical performance and...
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A Case of Severe Hemolytic Disease of the Newborn Due to Anti-Di(a) Antibody

Lee SM, Im SJ, Park SE, Lee EY, Kim HH

Here we report a severe case of hemolytic anemia of the newborn with kernicterus caused by anti-Di(a) antibody. A full term male infant was transferred due to hyperbilirubinemia on the...
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Prevalence of Extended-Spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae from Daejeon

Ko CS, Sung JY, Koo SH, Kwon GC, Shin SY, Park JW

BACKGROUND: Extended-spectrum beta-lactamases (ESBLs) are cephalosporinases that confer resistance to a wide variety of oxyimino cephalosporins and create serious therapeutic problems. Although ESBLs have been reported with increasing frequency...
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Clinical Significance of Quantitation of WT1 Gene Expression for Minimal Residual Disease Monitoring of Acute Myelogenous Leukemia

Kim HR, Shin JH, Lee JN, Lee EY

BACKGROUND: Following induction chemotherapy for AML, a sensitive determination of minimal residual disease (MRD) in patients achieving complete remission (CR) should enable the detection of early relapse. This study...
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Reconfirmation of Preanalytical Variables and Establishment of Reference Intervals of Platelet Function Analyzer-100 Closure Times in Korean Adults

Cho YU, Chi HS, Jang S, Park CJ

BACKGROUND: Platelet Function Analyzer-100 (PFA-100, Dade-Behring, Germany) is an instrument that simulates in vivo hemostatic plug formation under high shear flow by measuring the time required to occlude aperture....
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Evaluation of BioSewoom(TM) HLA-A, -B, -C PCR/SSP Kit

Cha CH, Kim MH, Chung HJ, Choi SE, Oh HB

BACKGROUND: Human leukocyte antigen (HLA) typing based on polymerase chain reaction (PCR) is rapidly replacing the conventional serological method. This study was intended to evaluate Bio- SewoomTM HLA-A, -B,...
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A Case of Bacteremia by Atopobium rimae in a Patient with Liver Cirrhosis

Chung HY, Sung H, Lee MY, Yoon NS, Lee SG, Suh DJ, Kim MN

Atopobium rimae, previously Lactobacillus rimae, is a strictly anaerobic, non-spore forming grampositive rod which was frequently isolated from odontogenic infection. We report a case of A. rimae bacteremia. A 47-yr-old...
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Analysis of Positive Results in Mediace Rapid Plasma Reagin and Treponema pallidum Latex Agglutination as the Automated Syphilis Test

Huh HJ, Lee KK, Kim ES, Chae SL

BACKGROUND: We compared the results of automated and quantitative methods for the diagnosis of syphilis, Mediace Rapid Plasma Reagin (RPR) and Mediace Treponema pallidum Latex Agglutination (TPLA) (Sekisui Chemical...
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Comparison of Cardiovascular Risk Factors between Normotension and Prehypertension

Nah EH, Kim HC

BACKGROUND: The individuals with prehypertension are known to progress to hypertension, one of the risk factors of cardiovascular disease, more readily than the group of normal blood pressure. This...
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