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Evaluation of Two Commercial HLA-B27 Real-Time PCR Kits

Cho EH, Lee SG, Seok JH, Park BY, Lee EH

BACKGROUND: The standard PCR with sequence-specific primers (SSP) is a widely used method of HLA-B27 typing in clinical practice. The aim of our study was to evaluate 2 Korean HLA-B27...
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Effectiveness of Sodium Fluoride as a Glycolysis Inhibitor on Blood Glucose Measurement: Comparison of Blood Glucose using Specimens from the Korea National Health and Nutrition Examination Survey

Lee YW, Cha YJ, Chae SL, Song J, Yun YM, Park HI, Seong MW, Whang DH, Kim HS, Kim JH, Lee BS, Hwang YS

BACKGROUND: Accurate measurement of blood glucose concentrations is essential for defining diabetes, and the minimization of ex vivo glycolysis has been recommended. Recent guidelines advocate two kinds of methods for...
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A Case of Immune Hemolytic Anemia Induced by Ceftizoxime and Cefobactam (Sulbactam/Cefoperazone)

Baek EJ, Lee S, Kim S, Choi HK, Kim HO

Simultaneous drug-induced immune hemolytic anemia (DIIHA) caused by multiple drugs is rare. We report a case of a patient who developed DIIHA caused by 2 drugs. The patient's serum exhibited...
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Perception of the Risks of Blood Transfusion in Koreans

Whang DH, Um TH, Ha M

BACKGROUND: The perceived risks of blood transfusions are important to be considered in creating a blood service policy. We surveyed the perception of blood transfusion risks among Korean laypeople. METHODS:...
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Evaluation of Platelet Indices for Differential Diagnosis of Thrombocytosis by ADVIA 120

Song YH, Park SH, Kim JE, Ahn JY, Seo YH, Park PH, Kim KH

BACKGROUND: For the diagnosis of essential thrombocythemia (ET), no single clinical or laboratory finding of diagnostic value is available and a differential diagnosis of other myeloproliferative neoplasms or reactive thrombocytosis...
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Near-tetraploidy Acute Myeloid Leukemia with RUNX1-RUNX1T1 Rearrangement Due to Cryptic t(8;21)

Im M, Lee JK, Lee DY, Hong YJ, Hong SI, Kang HJ, Chang YH

Tetraploidy or near-tetraploidy is a rare cytogenetic abnormality found in AML, and is divided into primary and secondary forms. The secondary tetraploidy or near-tetraploidy found in AML is known to...
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Hepatitis A Virus Seropositivity among Healthcare Workers at a University Hospital in Korea

Son JS, Lee MS, Kang SY, Lee WI

BACKGROUND: Healthcare workers (HCW) are known as a risk group of hepatitis A virus (HAV) infection and vaccination of this group against HAV has been suggested. However, the seroprevalence of...
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Frequent CD7 Antigen Loss in Aggressive Natural Killer-Cell Leukemia: A Useful Diagnostic Marker

Yoo EH, Kim HJ, Lee ST, Kim WS, Kim SH

BACKGROUND: Aggressive natural killer-cell leukemia (ANKL) is a rare neoplasm characterized by systemic proliferation of NK cells. However, the differential diagnosis of NK lymphoproliferative disorders is difficult because of the...
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An Experience of ABO-incompatible Kidney Transplantation Using Plasmapheresis and Anti-CD20 Monoclonal Antibody

Moon HW, Yun YM, Hur M, Park JH, Lee HW, Chang SH, Yun IJ

Due to an extreme shortage of cadaveric kidneys, many centers in Japan successfully performed ABO-incompatible kidney transplantations using plasmapheresis, splenectomy and immunosuppression. Recently, a protocol including anti-CD20 monoclonal antibody (rituximab)...
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Comparison of Diagnostic Utility between Procalcitonin and C-Reactive Protein for the Patients with Blood Culture-Positive Sepsis

Hur M, Moon HW, Yun YM, Kim KH, Kim HS, Lee KM

BACKGROUND: Procalcitonin (PCT) is a relatively new marker for bacterial infections, and its diagnostic utility has been variable across the studies. We investigated the diagnostic utility of PCT for the...
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Hemoglobin Yamagata: Hemoglobin Variant Detected by HbA1c Test

Jung CL, Kwon KJ, Hong KS, Sung YA, Lee ST, Ki CS, Lee MA, Chung WS

Hemoglobin (Hb) Yamagata is a rare Hb variant, which has been reported only twice-one case each in Japan and Korea. This variant arises from a Lys --> Asn substitution due...
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An Epidemiological Analysis of Hepatitis A Virus Serologic Markers during the Recent Four Years in Korea

Lee A, Lim HS, Nam CM, Song SM, Yoon HR, Lee KR

BACKGROUND: To establish effective preventive measures for hepatitis A virus (HAV) infection, a nationwide epidemiologic study on seroprevalence of anti-HAV and the disease prevalence is needed. The aim of this...
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Usefulness of Silica Clotting Time for Detection of Lupus Anticoagulants

Lee HR, Kim JE, Ha SH, Kim HK, Park S, Cho HI

BACKGROUND: The presence of lupus anticoagulants (LA) is a strong risk factor for thrombosis in antiphospholipid syndrome. We investigated the usefulness of addition of silica clotting time (SCT) to the...
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Determination of Plasma Warfarin Concentrations in Korean Patients and Its Potential for Clinical Application

Kwon MJ, Kim HJ, Kim JW, Lee KH, Sohn KH, Cho HJ, On YK, Kim JS, Lee SY

BACKGROUND: Warfarin is a widely used oral anticoagulant with broad within- and between-individual dose requirements. Warfarin concentrations can be monitored by assessing its pharmacologic effects on International Normalized Ratio (INR)....
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Characteristics of aac(6')-Ib-cr Gene in Extended-Spectrum beta-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolated from Chungnam Area

Shin SY, Kwon KC, Park JW, Song JH, Ko YH, Sung JY, Shin HW, Koo SH

BACKGROUND: Concomitant quinolone resistance in extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is a crucial problem in the clinical management of infections. In foreign countries, the fluoroquinolone acetylating aminoglycoside-(6)-N-acetyltransferase (aac[6']-Ib-cr) gene, a novel...
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Serologic Screening of Pregnant Korean Women for Primary Human Cytomegalovirus Infection Using IgG Avidity Test

Seo S, Cho Y, Park J

BACKGROUND: Primary human cytomegalovirus (CMV) infection during pregnancy is a major cause of congenital malformation. We detected primary CMV infection in pregnant Korean women by using an algorithm that comprises...
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Application of a Diagnostic Method Using Reverse Transcription-PCR ELISA for the Diagnosis of Enteroviral Infections

Park K, Lee K, Baek K, Jung E, Park S, Cho Y, Song J, Ahn G, Cheon DS

BACKGROUND: Enteroviruses are known as major pathogen for aseptic meningitis. Although rapid diagnosis for enteroviruses is very essential to exclude bacterial infections in patients with meningitis, classical diagnostic method based...
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