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A Case of 46,XY Pure Gonadal Dysgenesis with Loss of the Sex-Determining Region of Y Chromosome

Yoon KH, Lee YJ

A 23-yr-old phenotypic female was seen for primary amenorrhea. Her pubic hair was relatively well developed and external genitalia showed normal female appearance, but breast development was retarded. Transvaginal ultrasonographic...
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Current Status of Serum Allergen Tests in Korea

Lim HS, Kim HS, Oh H

BACKGROUND: Due to the westernization of living environments in Korea, a number of allergy patients are greatly increasing. External quality control assessments are difficult for allergy tests due to...
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Association of HLA-A, B antigens with Susceptibility to Advanced Endometriosis in Koreans

Whang DH, Kim SH, Park MH, Choi YM

BACKGROUND: Endometriosis is defined as the presence of endometrial tissue outside the uterus, causing diverse diseases, including infertility, pelvic pain, dysmenorrhea, and constipation. While there is a growing body...
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Meta-Analysis for the Pooled Sensitivity and Specificity of Hepatitis B Surface Antigen Rapid Tests

Hwang SH, Oh HB, Choi SE, Kim HH, Chang CL, Lee EY, Son HC

BACKGROUND: Although hepatitis B surface antigen (HBsAg) rapid test based on immunochromatographic assay (ICA) is now widely used, the test has not been evaluated sufficiently enough to validate its...
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Effect of Leukapheresis on Gene Expression Profiles of Donor's Peripheral Blood Mononuclear Cells

Shin JW, Jin P, Stroncek D

BACKGROUND: Leukapheresis has commonly been used to obtain the cell products intended for clinical cell therapy. Hypocalcemia related to citrate toxicity and some circulatory effects such as hypovolemia and...
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Effect of Nitric Oxide on the Cryopreservation of Platelets

Lee JH, Kim JT, Cho YG

BACKGROUND: To determine whether nitric oxide (NO) could inhibit activation of platelets stored in a cold or frozen state, we measured platelet P-selectin expression and platelet-bound fibrinogen in platelet-rich...
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A Case of Partial Trisomy 9pter --> q13 due to Paternal Balanced Translocation t (9;21) (q13;q21)

Woo KS, Kim KE, Kwon EY, Kim JP, Han JY

Trisomy 9p is one of the most frequent autosomal anomalies compatible with a long survival rate. Clinical characteristics are craniofacial dysmorphisms including hypertelorism, prominent nose, deepset eyes, and down-slanting palpebral...
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Detection of Rifampin Resistant Mycobacterium tuberculosis complex using Denaturing HPLC

Nam YH, Lee SH, Ahn YC, Cho MH, Jang WC, Park SM, Kwon PS, Kim JW

BACKGROUND: Tuberculosis (TB) remains an important cause of morbidity and mortality throughout the world. The surge of TB has been accompanied by an increase in multi-drug-resistant tuberculosis (MDR-TB). In...
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Performance Evaluation of Abbott RealTime HBV Quantification Kit for HBV Viral Load by Real-Time PCR

Kim MH, Cha CH, An D, Choi SE, Oh HB

BACKGROUND: Hepatitis B virus (HBV) DNA quantification is necessary for starting and monitoring of antiviral therapy in patients with chronic hepatitis B. This study was intended to assess the...
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Cytomorphology and Molecular Characterization of CLTC-ALK Rearrangement in 2 Cases of ALK-Positive Diffuse Large B-cell Lymphoma with Extensive Bone Marrow Involvement

Choung HS, Kim HJ, Kim WS, Kim K, Kim SH

Aanaplastic lymphoma kinase (ALK)-positive diffuse large B-cell lymphoma (DLBCL) is an unusual disease entity first reported in 1997 as DLBCL with expression of full-length ALK protein. The World Health Organization...
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Detection of Mycobacterium tuberculosis complex Using Real-time Polymerase Chain Reaction

Chang HE, Heo SR, Yoo KC, Song SH, Kim SH, Kim HB, Park KU, Song J, Lee JH, Park SS, Kim EC

BACKGROUND: For the detection of Mycobacterium tuberculosis complex (MTB), PCR is known to be sensitive, specific, and rapid compared to the conventional methods of acid-fast-bacilli (AFB) smear and culture....
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Evaluation of Seeplex(TM) RV Detection Kit for Detecting Rhinovirus, Human Metapneumovirus, and Coronavirus

Sung H, Park SJ, Woo YD, Choi BH, Kim MN

BACKGROUND: Direct antigen test (DAT) and culture are primary tests to diagnose infections by respiratory viruses, but are mainly available for the traditional viral pathogens such as respiratory syncytial...
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