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Plasmablastic Lymphoma Mistaken for Perianal Abscess in Patient with AIDS

Lee SC, Kim HJ, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Hong DS, Park HS, Jin SY, Won JH

Patients with acquired immunodeficiency virus (AIDS) are at increased risk for B-cell neoplasms and plasma cell dyscrasias. Plasmablastic lympomas (PBLs) were originally described exclusively in HIV-positive patients who presented with...
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A Case of Acute Lymphoblastic Leukemia Accompanied with Lactic Acidosis and Kidney Enlargement

Cho HS, Choi SO, Seol DC, Yoon HS, Jo YI, Lee HG

There have been several reported cases of acute lymphoblastic leukemia with severe lactic acidosis in adults. In these cases, kidney and liver enlargement that was caused by leukemic infiltration frequently...
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A Case of Desensitization for Hemophilia B Inhibitor Patient with Anaphylaxis to FIX Concentrates

Park Y, Yoo KY

Among the patients with hemophilia, 10~15% have hemophilia B, and 1~3% of the hemophilia B patients develop inhibitor to factor IX clotting activity. Allergic reactions to concentrates containing factor IX...
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All-trans Retinoic Acid-induced Nephrotic-range Proteinuria in a Patient with Acute Promyelocytic Leukemia

Lim SU, Lee SR, Seo SR, Ahn JS, Kim YK, Yang DH, Lee JJ, Kim HJ

All-trans retinoic acid (ATRA) is a potent differentiating agent for the treatment of acute promyelocytic leukemia (APL). Although ATRA is generally well-tolerated, some patients develop side effects, the most severe...
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A Case of Epstein-Barr Virus-positive Diffuse, Large B-cell Lymphoma after Angioimmunoblastic T-cell Lymphoma

Choi YH, Kim HS, Nam SB, Kang HJ, Na II, Yang SH, Ryoo BY

Angioimmunoblastic T-cell lymphoma (AITL) is a systemic lymphoproliferative disorder that presents with profound immune dysfunction and immunodeficiency. As in many other immunodeficiencies, Epstein-Barr virus (EBV) associated B-cell lymphoid proliferation can...
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Stromal Cell-Derived Factor-1 Promotes Myeloma Cell Growth in Both Autocrine and Paracrine Manners

Kim SW, Kim HY, Lee HJ, Yun HJ, Kim S, Jo DY

BACKGROUND: The question as to whether stromal cell-derived factor-1 (SDF-1) stimulated myeloma cell growth has been controversial. We explored the possibility that SDF-1 may function as an autocrine growth factor...
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A Case of Acquired Factor V Inhibitor

Kim SY, Kim HK, Kim SW, Cho HI

Acquired inhibitor of coagulation factor V is a rare clinical condition and may cause significant morbidity and mortality. We report here the first Korean case of acquired isolated factor V...
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Bortezomib Therapy Followed by Autologous Stem Cell Transplantation in POEMS Syndrome

Kang SH, Lee JY, Chun SH, Park HW, Min CK, Kim CC, Kim M, Kim Y

BACKGROUND: The acronym POEMS refers to polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes. Increased levels of cytokines, including vascular endothelial growth factor (VEGF), appear to play a pathogenic role....
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A Case of Central Nervous System Myelomatosis Developing after Allogeneic Hematopoietic Stem Cell Transplantation

Yun GW, Song IC, Jin SA, Yang YJ, Park NH, Lee HJ, Yun HJ, Kim S, Jo DY

Central nervous system (CNS) myelomatosis, which is the presence of monoclonal plasma cells in the cerebrospinal fluid (CSF), is extremely rare. We report a case of CNS myelomatosis developed in...
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VPDL Chemotherapy for T-cell Lymphoblastic Lymphoma (T-LBL) in Adults: Comparison with Upfront Autologous Stem Cell Transplantation in a Single Center

Yoon DH, Sohn BS, Lee WJ, Lim SN, Kim EK, Park I, Kim KM, Jang G, Kim S, Lee DH, Huh J, Suh C

BACKGROUND: Treatment of T-cell lymphoblastic lymphoma (T-LBL) with CHOP or CHOP-like chemotherapy has resulted in poor long-term outcomes. High-dose chemotherapy followed by ASCT has been applied for this dreaded disease....
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A Case of Atypical CML with Micro BCR/ABL Rearrangement

Kim JH, Lee WM, Ryoo NH, Ha JS, Jeon DS, Kim JR, Kwon KY

Microtype BCR/ABL rearrangement is extremely rare and has been known to be associated with neutrophilic chronic myeloid leukemia (N-CML). However, there is more to be understood regarding this phenotype. We...
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Comparison of Immune Responses Induced by Deferoxamine and Deferasirox

Jung YS, Bae EY, Chung NG, Cho B, Kim HK, Min CK, Han CW, Kim HS, Jeong DC

BACKGROUND: The iron chelating agents (ICA) have various biological effects besides iron chelation. We investigated the immunomodulatory effects of Deferasirox (DFS) compared to Deferoxamine (DFO). METHODS: Spleen cells (SP) were obtained...
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Complications of a Totally Implanted Vascular Access Device (Chemoport) in Children with Malignancy

Kim JO, Lee JH, Lee KS

BACKGROUND: Carefully using a totally implanted vascular access device and regular check-up of its condition in children who suffer with malignancy is very important. This study was performed to determine...
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