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Necklace-like microvacuoles of tumor cells in blastic plasmacytoid dendritic cell neoplasm

Hwang SM, Kim HK

No abstract available.
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The prospect of the government management for cord blood in Korea: at the time of enactment of the Cord blood management and research act

Lee YH

No abstract available.
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Plasma fractionation in Korea: working towards self-sufficiency

Park Q, Kim MJ, Lee J, Shin S

No abstract available.
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Refractory anemia with ring sideroblasts in a young individual

Cho JH, Hur M, Kim SY

No abstract available.
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A case of donor-derived granulocytic sarcoma after allogeneic hematopoietic stem cell transplantation

Jeong SH, Han JH, Jeong SY, Kang SY, Lee HW, Choi JH, Park JS

The occurrence of granulocytic sarcoma as a pattern of relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is rare. In this paper, we report a rare case of acute myeloid...
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Prognostic significance of nucleophosmin mutations and FLT3 internal tandem duplication in adult patients with cytogenetically normal acute myeloid leukemia

Kim YK, Kim HN, Lee SR, Ahn JS, Yang DH, Lee JJ, Lee IK, Shin MG, Kim HJ

BACKGROUND: Nucleophosmin (NPM1) gene and fms-like tyrosine kinase 3 gene-internal tandem duplication (FLT3-ITD) mutations are the most frequent mutations in patients with cytogenetically normal (CN)-AML. We analyzed the prognostic impact...
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Quality assessment of cellular therapies: the emerging role of molecular assays

Stroncek D, Jin P, Ren J, Feng J, Castiello , Civini S, Wang E, Marincola , Sabatino M

Cellular therapies are becoming increasingly important in treating cancer, hematologic malignancies, autoimmune disorders, and damaged tissue. These therapies are becoming more effective and are being used more frequently, but they...
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JAK2 V617F mutation in myelodysplastic syndrome, myelodysplastic syndrome/myeloproliferative neoplasm, unclassifiable, refractory anemia with ring sideroblasts with thrombocytosis, and acute myeloid leukemia

Jekarl DW, Han SB, Kim M, Lim J, Oh EJ, Kim Y, Kim HJ, Min WS, Han K

BACKGROUND: The JAK2 V617F mutation has been noted in the cases of polycythemia vera, essential thrombocythemia, and primary myelofibrosis patients. This mutation occurs less frequently in acute myeloid leukemia (AML)...
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Biological effects of fucoidan isolated from Fucus vesiculosus on thrombosis and vascular cells

Kwak KW, Cho KS, Hahn OJ, Lee KH, Lee BY, Ko JJ, Chung KH

BACKGROUND: Fucoidan is a highly sulfated glycosaminoglycan, which has a molecular structure similar to that of heparin. The antithrombotic effects of fucoidan in vitro have been widely reported, but its...
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A case of subdural hematoma in patient with chronic myeloid leukemia treated with high-dose imatinib mesylate

Kim MS, Lee DH, Lee YR, Kim DK, Bae SH, Hwang JY, Kwon KA, Lee S, Han JY, Kim KU, Kim SH

Imatinib mesylate (IM) is used to treat a wide range of diseases, including Philadelphia chromosome-positive chronic myeloid leukemia (CML), on account of its high tolerability and low incidence of minor...
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Efficacy and safety of deferiprone (Ferriprox), an oral iron-chelating agent, in pediatric patients

Won SC, Han DK, Seo JJ, Chung NG, Park SK, Park KB, Kook H, Lyu CJ

BACKGROUND: Iron overload is a predictable and life-threatening complication in patients dependent on the regular transfusion of RBCs. The aims of this study were to investigate the efficacy and safety...
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Synchronous development of KIT positive acute myeloid leukemia in a patient with gastrointestinal stromal tumor

Joo YB, Choi SH, Kim SK, Shim B, Kim MS, Kim YJ

We report a case of synchronous occurrence of KIT-positive acute myeloid leukemia (AML) and gastrointestinal stromal tumor (GIST). A 63-year-old woman was hospitalized for dizziness, and abdominal computed tomography revealed...
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Recent advances in the management of venous thromboembolism

Ageno W

Venous thromboembolism (VTE) is a spectrum of diseases that includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Anticoagulant treatment is the mainstay of therapy for VTE. Unfractionated heparin (UFH)...
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Usefulness of circulating vascular endothelial growth factor and neutrophil elastase as diagnostic markers of disseminated intravascular coagulation in non-cancer patients

Joo SY, Kim JE, Kim JY, Han KS, Kim HK

BACKGROUND: Disseminated intravascular coagulation (DIC) is characterized by platelet and neutrophil activation. Platelets are the major source of circulating vascular endothelial growth factor (VEGF). Endostatin, an anti-angiogenic factor, is a...
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Clinical and radiologic evaluation of cytomegalovirus-induced thrombocytopenia in infants between 1 and 6 months of age

Kang JW, Kim GN, Kim SY, Kim HJ, Park ES, Kim JY, Lee YH

BACKGROUND: Up to 90% of neonates with congenital or perinatal cytomegalovirus (CMV) infection are asymptomatic, and little is known about CMV-associated thrombocytopenia after the neonatal period. We investigated the clinical...
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Neostigmine for the treatment of acute colonic pseudo-obstruction (ACPO) in pediatric hematologic malignancies

Lee JW, Bang KW, Jang PS, Chung NG, Cho B, Jeong DC, Kim HK, Im SA, Lim GY

BACKGROUND: Acute colonic pseudo-obstruction (ACPO) refers to dilatation of the colon and decreased bowel motility without evidence of mechanical obstruction. Neostigmine, an acetylcholinesterase inhibitor, has been used in patients in...
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