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Epidemiological Change of Multiple Myeloma in Korea

Lee JH, Bang SM

Multiple myeloma is a hematologic neoplasm with a unique and characteristic manifestation. This condition is responsible for 10% of hematologic malignancies, and thus represents 1% of all cases of cancer...
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Identification of Leukemia Surface Proteins Using a Proteomic Technique

Park JI, Kim HI, Lee HW, Kang SY, Jang JH, Park JS, Choi JH, Lim HY, Kim HC

BACKGROUND: Numerous cell surface proteins of leukemia cells such as CD33 and CD52 have been identified as diagnostic and therapeutic targets. Thus the profiling of the cell surface proteome and...
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The Correlation between G-CSF Dosage and the Number of Collected CD34+ Cells in Pediatric Patients Undergoing Peripheral Blood Stem Cell Mobilization

Lee JS, Jung HJ, Park JE

BACKGROUND: In high risk malignancies of pediatric patients, many investigators have explored the use of stronger myeloablative regimens with autologous peripheral blood stem cell rescue such as the Tandem protocol....
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Outcome of Severe Aplastic Anemia Treated with Immunosuppressive Therapy Compared with Bone Marrow Transplantation

Kim HI, Baik SH, Yoo JH, Joe DY, Park JI, Lee HW, Kang SY, Jang JH, Park JS, Choi JH, Kim HC

BACKGROUND: The response rates and survival following allogeneic bone marrow transplantation (BMT) or immunosuppressive treatment were compared in severe aplastic anemia (SAA) and the prognostic factors related with survival identified. METHODS:...
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A Case of Autoimmune Hemolytic Anemia Treated with Rituximab in a Child

Lee JH, Lee KS

Autoimmune hemolytic anemia (AIHA) in children usually responds well to short-term steroid therapy. However, in some cases, AIHA requires prolonged immunosuppressive therapy, with the subsequent development of severe side effects....
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Intravascular Large B-cell Lymphoma with Bone Marrow Involvement: A Case Successfully Treated with a Rituximab-CHOP Combination Regimen

Lee TH, Song EK

Intravascular large B-cell lymphoma is rare and generally fatal. It is defined pathologically by neoplastic proliferation of lymphoid cells within the lumens of capillaries, small veins, and arteries with little...
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A Case of Chronic Active Epstein-Barr Virus Infection with Autoimmnune Hepatitis and a Coronary Aneurysm

Kim MJ, Lee JJ, Park KS, Kim SY, Kil HR

Infectious mononucleosis caused by primary infection of Epstein-Barr virus (EBV) is a self-limiting lymphoproliferative disease, and shows concomitant clinical features such as pyrexia, anorexia, sore throat, cervical lymphadenopathy, liver dysfunction...
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Autoimmune Hemolytic Anemia in Myelodysplastic Syndrome

Shim KY, Roh MO, Kim HJ, Bae SB, Kim CK, Lee KT, Lee YK, Park SK, Won JH, Park HS, Hong DS

Autoimmune paraneoplastic syndromes are encountered in patients with myelodysplastic syndromes. A review of case reports suggested 10% of myelodysplastic syndrome patients may experience various autoimmune syndromes, associated with immunological-mediated hematologic...
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Ten-year Experience on Acute Promyelocytic Leukemia at Inha University Hospital

Yi HG, Lim JH, Kim JS, Park HJ, Moon Y, Lee MH, Nahm CH, Kim CS

BACKGROUND: Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia in its morphology as well as molecular or genetic profiles, conferring a good prognosis owing to the...
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A Case of Acute Promyelocytic Leukemia after Iodine-131 Treatment for Thyroid Cancer

Lee SH, Eom KS, Lee S, Kim HJ, Min CK, Kim SY, Cho BS, Lee H, Park CK, Cho SG, Kim DW, Lee JW, Min WS, Kim CC

Radioactive iodine (131I) has been used in the treatment of thyroid cancer to eliminate residual thyroid tissue after thyroidectomy and to treat metastatic disease. Leukemia has rarely been reported as...
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Current Status of Hematopoietic Stem Cell Transplantation in Korean Children

Jeong DC, Kang HJ, Koo HH, Kook H, Kim SY, Kim SK, Ghim T, Kim HK, Kim HM, Moon HN, Park KD, Park BK, Park SG, Park YS, Park HJ, Seo JJ, Sung KW, Shin HY, Ahn HS, Ryu KH, Ryu KH, Yoo ES, Lyu CJ, Lee KC, Lee SY, Lee YH, Lim YT, Lim JY, Jang PS, Jeon IS, Chung NG, Cho B, Hah JO, Hwang PH, Hwang TJ

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is one of the most important armamentarium against various hematologic malignancies or some solid tumors. We investigated the number of patients who might need...
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Survival and Graft versus Host Disease in Murine MHC Mismatched Hematopoietic Stem Cell Transplantation with Co-injection of Mesenchymal Stem Cells

Choi S, Lee DH, Jeong DC, Hwang HS, Chung NG, Cho B, Han CW, Kim HK

BACKGROUND: Intravenous injection of mesenchymal and hematopoietic stem cells (MSCs, HSCs) has the disadvantages of low delivery rate to bone marrow and sequestration of cells in the lung and liver....
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A Case of Limbic Encephalitis Developed after Allogeneic Stem Cell Transplantation

Park NS, Park SE, Chun JM, Park NH, Yang YJ, Yun KW, Son EH, Yun HJ, Jo DY, Song CJ, Kim S

Limbic encephalitis is a rare neurological syndrome, which develops after stem cell transplantation, and is characterized by a series of neurological symptoms, including retrograde amnesia, behavioral disturbance, and progressive intellectual...
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Prospective Randomized Comparative Observations of Infectious Complications with or without Antimicrobial Prophylaxis, during Autologous Stem Cell Transplantation

Koo DH, Ko OB, Kim S, Lee DH, Kim SW, Suh C

BACKGROUND: A prospective randomized comparative observation was performed to assess the benefit of prophylactic antimicrobials in autologous stem cell transplantation (ASCT). METHODS: Forty consecutive patients, with multiple myelomas (MM, 28...
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Clinical Features of Pregnancy and Delivery in Patients with Idiopathic Thrombocytopenic Purpura

Jang MJ, Bae YH, Oh SY, Chong SY, Shin SJ, Chang SW, Oh D

BACKGROUND: Patients with the condition of idiopathic thrombocytopenic purpura (ITP) may present with, maternal and fetal hemorrhagic complications. Appropriate monitoring and treatment may be important in obstetric management. METHODS: A...
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