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Two Cases of Fulminant Type 1 Diabetes

Lee YM, Kweon KH, Baek SH, Kim HY, Park BH, Cho CG

  • KMID: 2177771
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):378-382.
Type 1 diabetes is characterized by insulin deficiency due to destruction of pancreatic beta-cells. Patients with type 1 diabetes, with no islet autoantibodies, but with acute onset, are classified as...
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Relationship between Carotid Atherosclerosis and Chlamydia Pneumoniae Seropositivity in Type 2 Diabetes

Jung SJ, Kim JH, Park JH, Park TS, Baek HS

  • KMID: 2177768
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):352-357.
BACKGROUND: The major causes of death in diabetic patients are atherosclerosis-related diseases. Infection with Chlamydia pneumoniae(C. pneumoniae) has been reported to play a pathogenic role in atherosclerosis. However, data relating...
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Clinical Meaning of Postprandial Insulin Secretory Function in Korean Type 2 Diabetes Mellitus

Shim WS, Kim SK, Kim HJ, Park SE, Kang ES, Rhee YM, Ahn CW, Lim SK, Kim KR, Lee HC, Cha BS

  • KMID: 2177770
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):367-377.
BACKGROUND: Impaired pancreatic beta-cell responsiveness is associated with type 2 diabetes mellitus. Postprandial insulin deficiency is closely related with fasting plasma glucose, HbA1c and insulin responses to meals, but most...
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Effect of Pinitol on Glucose Metabolism and Adipocytokines in Uncontrolled Type 2 Diabetes Mellitus

Kim MJ, Yoo KH, Park HS, Chung SM, Chin CJ, Choi YS, Chung CH

  • KMID: 2177766
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):344-351.
BACKGROUND: Pinitol(3-O-methyl-D-chiro-inositol) has been identified in putative insulin mediator fractions possessing hypoglycemic activity, and appears to act downstream in the insulin-signaling pathway to mimic the effects of insulin. We evaluated...
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Glutathion S-Transferase M1 Gene Polymorphism is Associated with Type 2 Diabetic Nephropathy

Kim JH, Moon MK, Kim SW, Shin HD, Hwang YH, Ahn C, Jang HC, Park KS, Kim SY, Lee HK

  • KMID: 2177759
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):315-321.
BACKGROUND: Oxidative stress may be a determinant of the development of diabetic nephropathy. Glutathione S-transferases(GST) can work as an endogenous antioxidant to protect cells from oxidative stress. Homozygous deletion of...
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Protective Effects of Lithospermate B on Diabetic Nephropathy in OLETF Rat

Lee HJ, Lee GT, Kang ES, Hur KY, Zhao ZS, Ahn CW, Ha HJ, Jung MK, Cha BS, Lee HC

  • KMID: 2177760
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):322-332.
BACKGROUND: Magnesium lithospermate B(LAB), an active component isolated from Salvia milltiorrhizae, has been reported to have renoprotective effects in type 1 diabetic animal model. The purpose of this study was...
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Clinical Characteristics and Analysis of Risk Factor for Gastroesophageal Reflux Disease in Diabetic Patient

Park KH, Yoon SB, Jo MH, Hong EK, Lee SJ, Jeong IK, Park CY, Oh KW, Kim HK, Yu JM, Kim DM, Lim SH, Choi MK, Yoo HJ, Park SW, Oh HY, Kim JB, Baek IH, Lee MS

  • KMID: 2177769
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):358-366.
BACKGROUND: A high prevalence of gastroesophageal reflux disease(GERD) has been reported in diabetic patient. However, the exact mechanisms of GERD in diabetic patient have not been described. In several studies,...
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The Role of cAMP/PKA Activation on Exendin-4-Induced Cyclin D1 Expression in INS-1 Cell

Ryu GR, Kang JH, Jang HI, Ko SH, Jeong IK, Rhie DJ, Yoon SH, Hahn SJ, Jo YH, Kim MS, Kim MJ

  • KMID: 2177757
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):295-303.
BACKGROUND: Glucagon-like peptide-1(GLP-1) and exendin-4(EX-4) have been known to induce pancreatic islet proliferation and increases in the betacell mass. Cyclin D1 is a key protein responsible for the entry of...
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Effective Glycemic Control Achieved by the Transplantation of VEGF-Transfected Islets in STZ-induced Diabetic Mice

Lee BW, Chae HY, Ahn YR, Oh SH, Kim JY, Chung YJ, Kim SY, Cho KY, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

  • KMID: 2177756
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):282-294.
BACKGROUND: Hypoxic damage is one of the major causes of early islet graft failure, and VEGF is known to play a crucial role in revascularization. We tried to evaluate whether...
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Disturbed Shear Stress Induces Inflammation and Atherosclerosis-Role of BMP4 as a Mechanosensitive and Inflammatory Cytokine

Jo H, Song H

  • KMID: 2177755
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):271-281.
Atherosclerosis is an inflammatory disease occurring preferentially in arterial regions exposed to disturbed flow conditions including oscillatory shear stress(OS). In contrast, the arterial regions exposed to laminar shear(LS) are relatively...
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Relationship of LDL Particle Size to IMT and Insulin Resistance in Non-Diabetic Adult

Park J, Kim CS, Park JS, Kim DM, Cho MH, Kong JH, Kim HJ, Kim JH, Ahn CW, Kim KR, Cha BS, Lim SK, Lee HC

  • KMID: 2177761
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):333-343.
BACKGROUND: The aims of this study were to investigate the predictor of the low density lipoprotein(LDL) particle size and the relationship of the LDL particle size to the levels of...
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Pancreatic Stellate Cell Activation by High Glucose and Its Effect on Angiotensin II

Ko SH, Hong OK, Lee MK, Park EH, Lee SS, Ahn YB, Song KH, Cha BY, Son HY, Kim MJ, Jung IK, Yoon KH

  • KMID: 2177758
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):304-314.
BACKGROUND: Pancreatic stellate cells (PSCs) are known to be related to pancreatic inflammation and fibrosis, and are the result of extracellular matrix(ECM) protein synthesis. Recent studies have shown that blockade...
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