- Prostaglandin D2 and TH2 Inflammation in the Pathogenesis of Bronchial Asthma
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Arima M, Fukuda T
- KMID: 1036144
- Korean J Intern Med.
- 2011 Mar;26(1):8-18.
- doi: 10.3904/kjim.2011.26.1.8
Prostaglandin D2 (PGD2) is a major prostanoid, produced mainly by mast cells, in allergic diseases, including bronchial asthma. PGD2-induced vasodilatation and increased permeability are well-known classical effects that may be... -
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- Overexpression of CIITA in T Cells Aggravates Th2-Mediated Colitis in Mice
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Kim TW, Park HJ, Choi EY, Jung KC
- KMID: 1781909
- J Korean Med Sci.
- 2006 Oct;21(5):877-882.
- doi: 10.3346/jkms.2006.21.5.877
The MHC class II transactivator (CIITA) is the master transcriptional regulator of genes involved in MHC class II restricted antigen presentation. Previously we suggested another role of CIITA in Th1/Th2... -
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- Mast cells play a key role in Th2 cytokine-dependent asthma model through production of adhesion molecules by liberation of TNF-alpha
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Chai OH, Han EH, Lee HK, Song CH
- KMID: 991621
- Exp Mol Med.
- 2011 Jan;43(1):35-43.
- doi: 10.3858/emm.2011.43.1.004
Mast cells are well recognized as key cells in allergic reactions, such as asthma and allergic airway diseases. However, the effects of mast cells and TNF-alpha on T-helper type 2... -
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- Protease-Activated Receptor 2 Is Involved in Th2 Responses against Trichinella spiralis Infection
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Park MK, Cho MK, Kang SA, Park HK, Kim YS, Kim KU, Ahn SC, Kim DH, Yu HS
- KMID: 1715646
- Korean J Parasitol.
- 2011 Sep;49(3):235-243.
- doi: 10.3347/kjp.2011.49.3.235
In order to get a better understanding of the role of protease-activated receptor 2 (PAR2) in type 2 helper T (Th2) cell responses against Trichinella spiralis infection, we analyzed Th2... -
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- IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model
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Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK
- KMID: 1104380
- Exp Mol Med.
- 2010 Aug;42(8):533-546.
- doi: 10.3858/emm.2010.42.8.054
IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream... -
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- Effect of German chamomile oil application on alleviating atopic dermatitis-like immune alterations in mice
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Lee SH, Heo Y, Kim YC
- KMID: 1106155
- J Vet Sci.
- 2010 Mar;11(1):35-41.
- doi: 10.4142/jvs.2010.11.1.35
Historically, German chamomile (GC) oil has been used for treatment of skin disorders. BALB/c mice were sensitized twice a week with 100 microL of 1% 2,4-dinitrochlorobenzene (DNCB) and challenged twice... -
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