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Effect of in vivo administration of Tetrahymena pyriformis on the in vitro toxoplasmacidal activity of mouse peritoneal macrophages

Kim CT, Chung PR, Im KI

Tetrahymena pyriformis is a free-living ciliate protozoan in the freshwater system. Experiments were carried out to determine whether intraperitoneal administration of T. pyriformis (GL strain) to mice activates macrophages to...
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Non-specific activation of mouse peritoneal macrophages by a freshwater ciliate, Tetrahymena pyriformis

Jung Y, Kim KS, Chung PR

Toxoplasma-killing activities of mouse peritoneal macrophages activated by the extracts of Tetrahymena pyriformis (Korean and Chinese strains) were evaluated, and the active protein fractions from both strains were partially characterized...
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Functional Modification of a Specific RNA with Targeted Trans-Splicing

Park YH, Kim SC, Kwon BS, Jung HS, Kimm K, Lee SW

  • KMID: 1974010
  • Genomics Inform.
  • 2004 Mar;2(1):45-52.
The self-splicing group I intron from Tetrahymena thermophila has been demonstrated to perform splicing reaction with its substrate RNA in the trans configuration. In this study, we explored the potential...
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In vitro toxicity of melamine against Tetrahymena pyriformis cells

Wang Z, Chen L, Al-Kasir R, Han B

This study assessed the toxicity of melamine against the unicellular eukaryotic system of Tetrahymena (T.) pyriformis exposed to 0, 0.05, 0.25, 0.5, 2.5, and 5 mg/mL of melamine. Cell growth...
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Specificity of Intracellular Trans-Splicing Reaction by hTERT-Targeting Group I Intron

Jung HS, Kwon BS, Lee SW

  • KMID: 2284678
  • Genomics Inform.
  • 2005 Dec;3(4):172-174.
Recent anti-cancer approaches have been based to target tumor-specifically associated and/or causative molecules such as RNAs or proteins. As this specifically targeted anti-cancer modulator, we have previously described a novel...
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In Vivo Target RNA Specificity of Trans-Splicing Phenomena by the Group I Intron

Song MS, Lee SW

  • KMID: 2166344
  • Genomics Inform.
  • 2008 Jun;6(2):84-86.
The Tetrahymena group I intron has been shown to employ a trans-splicing reaction and has been modified to specifically target and replace human telomerase reverse transcriptase (hTERT) RNA with a...
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Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach

Sood D, Kumar N, Singh A, Sakharkar , Tomar V, Chandra R

Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial infections in the field of both human and veterinary...
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