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Neurotoxic Effects of Tetrahydroisoquinolines and Underlying Mechanisms

Surh YJ, Kim HJ

Tetrahydropapaveroline (THP), a neurotoxic tetrahydroisoquinoline alkaloid formed by condensation between dopamine and dopaldehyde, has been speculated to cause Parkinson's disease and also to contribute to alcohol dependence. Having two catechol...
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