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Systematic Target Screening Revealed That Tif302 Could Be an OffTarget of the Antifungal Terbinafine in Fission Yeast

Lee S, Nam M, Lee AR, Lee J, Woo J, Kang NS, Balupuri A, Lee M, Kim SY, Ro H, Choi YW, Kim DU, Hoe KL

We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of the antifungal terbinafine, which inhibits ergosterol...
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In vitro Susceptibility of the Six Malassezia Species to Itraconazole, Fluconazole and Terbinafine

Lee Y

BACKGROUND: Malasseiza species are dimorphic and lipophilic fungi which are part of normal mycota of the human skin, and also associated with some skin diseases. In many skin diseases such...
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Systemic Antifungal Drugs for Onychomycosis

Kim H, Park SH, Kim KH

Onychomycosis is a common disease that requires appropriate management. Systemic antifungal agents are current standard for onychomycosis treatment. Considering high recurrence rate, selection of the systemic antifungal agent should be...
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Acute Generalized Exanthematous Pustulosis Caused by Terbinafine

Park SH, Chae JK, Kwon SY, Park K, Park SD

  • KMID: 2246232
  • Korean J Dermatol.
  • 2015 Feb;53(2):152-156.
A 12-year-old girl visited our clinic with pruritic non-follicular pustules on reddish bases and scales on her face, trunk, and proximal extremities. She complained of fever and chills. Before she...
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Taste Disturbance: An Unfamiliar Side Effect Associated with the Familiar Antifungal Agent, Terbinafine

Jeong YI, Huh JW, Kim G, Choi KH, Park HJ, Jue MS

  • KMID: 2129423
  • Korean J Dermatol.
  • 2015 Nov;53(9):730-732.
Terbinafine is a highly effective oral antifungal agent that is used to treat dermatophyte infections of the skin and nails. Although generally well tolerated, common side effects of terbinafine include...
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Prolonged Drug-Drug Interaction between Terbinafine and Perphenazine

Park YM

  • KMID: 2316237
  • Psychiatry Investig.
  • 2012 Dec;9(4):422-424.
I report here an elderly woman receiving perphenazine together with terbinafine. After 1 week of terbinafine treatment she experienced extrapyramidal symptoms and, in particular, akathisia. Her symptoms did not disappear...
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The Studies on the Concomitant Diseases and Combined Medication in Patients with Onychomycosis

Song YC, Ahn KJ, Kim HO, Kye YC, Choi JH, Park CW, Kim KJ

  • KMID: 1513557
  • Korean J Med Mycol.
  • 2007 Sep;12(3):163-172.
OBJECTIVE: We performed this survey to provide the information about how many patients with onychomycosis have concomitant diseases and combined medication and to gauge about the drug interaction risk of...
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The Long Term Efficacy and Relapse Rate of Itraconazole Pulse Therapy Versus Terbinafine Continuous Therapy for Toenail Onychomycosis: a 96-week follow-up study

Won CH, Lee J, Li K, Choi MR, Kim BJ, An JS, Kim KH, Cho SY, Moon SE, Kim JA, Eun HC

  • KMID: 1513554
  • Korean J Med Mycol.
  • 2007 Sep;12(3):139-147.
No abstract available.
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Generalized Pustular Psoriasis and Hepatic Dysfunction Associated with Oral Terbinafine Therapy

Kim BS, Jang HS, Jwa SW, Jang BS, Kim MB, Oh CK, Kwon YW, Kwon KS

We report a case of 61-yr-old man with stable psoriasis who progressively developed generalized pustular eruption, erythroderma, fever, and hepatic dysfunction following oral terbinafine. Skin biopsy was compatible with pustular...
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Erythema Nodosum Developed in a Child with Kerion Celsi

Ahn SY, Bak H, Choi EH

  • KMID: 2302151
  • Korean J Dermatol.
  • 2007 Oct;45(10):1101-1104.
A 7 year-old boy visited our hospital with a 2 week history of inflammatory, pustular, tender patches and plaques on the right scalp and face area. He had been treated...
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Two Cases of Anti-Ro and La Antibody-positive Cutaneous Lupus Erythematosus Probably Caused by Terbinafine

Kim JW, Kang HW

  • KMID: 1891830
  • Korean J Dermatol.
  • 2006 Feb;44(2):201-205.
Terbinafine is a drug for dermatophytosis, which is considered to be safe. However, susceptible patients are predisposed to drug-induced or exacerbated cutaneous lupus erythematosus (CLE). Herein, we describe two patients...
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The Compliance and Long-term Follow up of Onychomycosis Treatment

Kim JE, Park HJ, Lee JY, Cho BK

  • KMID: 1517379
  • Korean J Med Mycol.
  • 2003 Sep;8(3):110-117.
BACKGROUND: Modern antifungal drugs achieve high cure rates in onychomycosis of the toes, but little is known about the long-term evolution of the treated patients. OBJECTIVE: We evaluated the compliance...
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A Case of Chromoblastomycosis Treated with Terbinafine

Lee CW, Sim SJ, Song KH, Kim KH

  • KMID: 2080356
  • Korean J Med Mycol.
  • 2003 Mar;8(1):26-29.
Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissues caused by pigmented or dematiaceous fungi that are implanted into the dermis from the external environment. The vast...
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Deep Neck Infection due to Severe Neutropenia induced by Terbinafine in a Patient with Systemic Lupus Erythematosus

Yang JT, Cho YS, Joo YC, Jang DY, Kim JO, Koh HK

  • KMID: 1598562
  • J Korean Rheum Assoc.
  • 2002 Jun;9(2):137-140.
Terbinafine, a fungicidal agent used for the treatment of onychomycosis, has been found to be safe and adverse effects are usually mild and transient. Neutropenia is a rare side effect...
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The Compliance of Oral Antifungal Therapy in the Patients with Toenail Onychomycosis in Daegu Area: Comparison between Terbinafine Continuous Therapy and Itraconazole Pulse Therapy

Kim KH, Jeong KB, Choi JS, Kim DW, Jun JB, Song JY

  • KMID: 2307086
  • Korean J Med Mycol.
  • 2002 Dec;7(4):217-223.
BACKGROUND: The treatment of toenail onychomycosis requires a long term oral medication of antifungal agent, and its compliance is one of the important factors for the treatment of toenail onychomycosis. OBJECTIVE:...
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A Case of Kerion Celsi in the Elderly Caused by Trichophyton verrucosum and Treated with Terbinafine

Kim YJ, Choi JH, Bang JS, Suh MK, Lee JW, Kim TH, Ha GY, Kim JR

  • KMID: 2307101
  • Korean J Med Mycol.
  • 2000 Sep;5(3):129-134.
Kerion celsi presents as an inflammatory, boggy mass studded with broken hairs, oozing purulent material from follicular orifices. This infection is caused most commonly by zoophilic or geophilic dermatophytes and...
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Kerion Celsi Caused by Trichophyton verrucosum: A Report of Two Cases

Youn CS, Moon SH, Kim JA, Kim KH, Cho KH, Kang SH

  • KMID: 1575526
  • Korean J Med Mycol.
  • 2000 Jun;5(2):60-65.
In Korea, kerion celsi caused by Trichophyton(T.) verrucosum was first reported in the Honam area in 1986. Since then, more cases have been reported in the Youngnam and Chungcheong areas...
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Acute generalized exanthematous pustulosis induced by terbinafine

Ham SH, Ha SJ, Park YM, Cho SH, Kim JW

  • KMID: 2286164
  • J Asthma Allergy Clin Immunol.
  • 1998 Jun;18(2):330-334.
Terbinafine is now widely used for the treatment of dermatophytic infections of the skin and nails. Cutaneous side effects of terbinafine are rare and mild. They includes erythema, pruritus, urticaria, desqumation, and...
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A Case of Black Dot Ringworm Caused by Trichophyton violaceum

Lee JB, Kwon KS, Chung TA, Jang HS, Oh CK

  • KMID: 1855462
  • Korean J Med Mycol.
  • 1998 Jun;3(1):39-42.
Tinea capitis is a dermatophytosis of the scalp and associated hairs that is caused by the species of genera Mecrosporum and Trichophyton. It commonly affects children. Black dot ringworm (BDR)...
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A Case of Cutaneous Disseminated Type of Sporotrichosis Resistant to Itraconazole and Terbinafine

Kim DS, Kim JW, Kim SW

  • KMID: 1549925
  • Korean J Med Mycol.
  • 1997 Dec;2(2):169-173.
Sporotrichosis, a deep fungal infection caused by Sporothrix schenckii, is mainly treated with potassium iodide (Kl) and other antifungal agents, and recently there were reports of cases treated with itraconazole...
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