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Central Nervous System Infection-Related Isolated Hippocampal Atrophy as Another Subtype of Medial Temporal Lobe Epilepsy with Hippocampal Atrophy: A Comparison to Conventional Medial Temporal Lobe Epilepsy with Hippocampal Atrophy

Park S, Kim WJ, Lee SK, Chang JW

Background and Purpose: Hippocampal atrophy (HA) resulting from a central nervous system (CNS) infection might be a relevant lesion responsible for the clinical characteristics of medial temporal lobe epilepsy. Methods: The...
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Clinical Usefulness of Intraoperative Motor-Evoked Potential Monitoring during Temporal Lobe Epilepsy Surgery

Koo DL, Lee WG, Hong SC, Seo DW

BACKGROUND AND PURPOSE: We aimed to determine the effectiveness of intraoperative neurophysiological monitoring focused on the transcranial motor-evoked potential (MEP) in patients with medically refractory temporal lobe epilepsy (TLE). METHODS: We...
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Antiepileptic and anti-neuroinflammatory effects of red ginseng in an intrahippocampal kainic acid model of temporal lobe epilepsy demonstrated by electroencephalography

Kim JY, Kim JH, Lee HJ, Kim SH, Jung YJ, Lee HY, Kim HJ, Kim SY

BACKGROUND: Chronic inflammation can lower the seizure threshold and have influence on epileptogenesis. The components of red ginseng (RG) have anti-inflammatory effects. The abundance of peripherally derived immune cells in...
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A Case of Phantosmia Occurred by Glioblastoma

Lee SY, Kim JW

Phantosmia is defined as the false perception of odors without any environmental odor stimulus. It is a very rare phenomenon, but it can be caused by a wide variety of...
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Structural and Functional Alterations at Pre-Epileptic Stage Are Closely Associated with Epileptogenesis in Pilocarpine-induced Epilepsy Model

Kim H, Choi Y, Joung HY, Choi YS, Kim HJ, Joo Y, Oh JH, Hann HJ, Cho ZH, Lee HW

Pilocarpine-induced rat epilepsy model is an established animal model that mimics medial temporal lobe epilepsy in humans. The purpose of this study was to investigate neuroimaging abnormalities in various stages...
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Asymmetric Gray Matter Volume Changes Associated with Epilepsy Duration and Seizure Frequency in Temporal-Lobe-Epilepsy Patients with Favorable Surgical Outcome

Kim JS, Koo DL, Joo EY, Kim ST, Seo DW, Hong SB

BACKGROUND AND PURPOSE: This study aimed to estimate the changes in gray matter volume (GMV) and their hemispheric difference in patients with mesial temporal lobe epilepsy (MTLE) using a voxel-based...
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Changes in Central Auditory Processing in Patients with Mesial Temporal Lobe Epilepsy after Anterior Temporal Lobectomy with Amygdalohippocampectomy

Han SH, Lee EM, Choi EJ, Ryu HU, Kang JK, Chung JW

BACKGROUND AND PURPOSE: This study aimed to determine the effects of anterior temporal lobectomy with amygdalohippocampectomy (ATL-AH) on central auditory processing (CAP) in patients with mesial temporal lobe epilepsy with...
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Modulation of axonal sprouting along rostro-caudal axis of dorsal hippocampus and no neuronal survival in parahippocampal cortices by long-term post-lesion melatonin administration in lithium-pilocarpine model of temporal lobe epilepsy

Kazemi M, Shokri S, Ganjkhani , Ali R, Iraj JA

Feature outcome of hippocampus and extra-hippocampal cortices was evaluated in melatonin treated lithium-pilocarpine epileptic rats during early and chronic phases of temporal lobe epilepsy (TLE). After status epilepticus (SE) induction,...
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Psychiatric Symptoms in Temporal Lobe Epilepsy with Left Mesial Hippocampal Sclerosis

Jang H, Kim SH, Park SH, Choo IH, Kim SG

A 16-year-old woman was referred to us for depression and persistent suicidal and homicidal ideation. From 2010, the patient visited a neurologist due to recurrent grand mal epilepsy, auditory and...
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Temporal lobe epilepsy surgery in children versus adults: from etiologies to outcomes

Lee YJ, Lee JS

Temporal lobe epilepsy (TLE) is the most common type of medically intractable epilepsy in adults and children, and mesial temporal sclerosis is the most common underlying cause of TLE. Unlike...
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The Lateralization and Localization of Memory and Neurocognitive Functioning in Patients with Temporal Lobe Epilepsy

Shin MS, Seol SH, Lee SK, Chung CK

  • KMID: 2008768
  • J Korean Epilepsy Soc.
  • 2012 Jun;16(1):14-25.
PURPOSE: Material-specific memory deficits (laterality effects) are frequently observed in patients with temporal lobe epilepsy (TLE), and yet the different functional roles of temporal cortical vs. mesial structures remain unclear....
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Current-Source Dipole of Anterior Temporal Spikes: Clinical Significance of Orientation

Kim YS, Kwon OY, Jung S, Son S, Kim S, Kang H, Park KJ, Choi NC, Lim BH

  • KMID: 2343399
  • J Korean Neurol Assoc.
  • 2011 Aug;29(3):165-171.
BACKGROUND: The voltage topography of temporal spikes has two distinct patterns, designated type I and type II; the orientation of the current-dipole source (O-CDS) of type I spikes tends to...
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Gray, White Matter Concentration Changes and Their Correlation with Heterotopic Neurons in Temporal Lobe Epilepsy

Tae WS, Joo EY, Kim ST, Hong SB

OBJECTIVE: To identify changes in gray and white matter concentrations (GMC, WMC), and their relation to heterotopic neuron numbers in mesial temporal lobe epilepsy (mTLE). MATERIALS AND METHODS: The gray matter...
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Language Lateralization in Patients with Temporal Lobe Epilepsy : A Comparison between Volumetric Analysis and the Wada Test

Oh YM, Koh EJ

OBJECTIVE: Determining language lateralization is important for the presurgical evaluation of patients with medically intractable epilepsy. The Wada test has been the gold standard for lateralization of language dominance before...
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Clinico-Electrographic Concordance Between Monozygotic Twins with Temporal Lobe Epilep

Lee SJ, Park MS, Noh HD

  • KMID: 1470051
  • J Korean Epilepsy Soc.
  • 2009 Jun;13(1):19-21.
We report a monozygotic twins with temporal lobe epilepsy, almost concordant in the onset time of firt seizure, lateralization and localization of epileptiform discharges. Partial seizures with secondarily generalized seizure...
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Postoperative Electroclinical Features in Epilepsy Patients With Seizures After Anteromesial Temporal Resection

Seo DW

  • KMID: 2343325
  • J Korean Neurol Assoc.
  • 2008 Nov;26(4):314-322.
BACKGROUND: Anteromesial temporal resection (AMTR) is well established as effective in patients with intractable mesial temporal epilepsy. However, little electroclinical information is available relevant to poor surgical outcome after AMTR....
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Transient Hyperorality during Automotor Seizure in a Patient with Right Temporal Lobe Epilepsy. Epileptic Kluver-Bucy Syndrome?

Jung KY, Han SG, Seo DW

  • KMID: 2181935
  • J Korean Epilepsy Soc.
  • 2008 Jun;12(1):59-61.
Kluver-Bucy Syndrome (KBS) is consisting of hyperorality, emotional blunting, hypersexuality, altered dietary habits, visual and auditory agnosia. It has been reported in variable neurological diseases. However, only a few cases...
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Clinical Factors Related With Response to Anti-epileptics in Temporal Lobe Epilepsy With Hippocampal Sclerosis

Yang HW, Lee W, Jung YT, Hwang TG, Kim SE

  • KMID: 2065661
  • J Korean Neurol Assoc.
  • 2008 May;26(2):104-109.
BACKGROUNDS: Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is not always intractable to antiepileptic drugs (AEDs). To identify the responsiveness to AEDs and related clinical factors in TLE-HS, we performed...
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Ictal Nose Wiping in a Patient with Mesial Temporal Lobe Epilepsy

Koh HS, Cho YJ, Jang SH, Chang JW, Lee BI, Heo K

  • KMID: 2063593
  • J Korean Epilepsy Soc.
  • 2007 Dec;11(2):109-112.
Seizure-associated nose wiping occurs usually during postictal period and is more frequent in temporal than extratemporal lobe epilepsy. The hand used to wipe the nose is highly suggestive of ipsilateral...
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Clinical Characteristics of Temporal Lobe Epilepsy in Childhood

Jeong GU, Cho AN, Lee JS, Park JY, Moon JH, Hwang H, Hwang YS, Kim KJ, Chae JH

  • KMID: 2329580
  • J Korean Child Neurol Soc.
  • 2006 Nov;14(2):276-285.
PURPOSE:Temporal lobe epilepsy(TLE) is now recognized as a distinct syndrome in adults. The seizure evolution in adult patients is well characterized, manifesting initially with an aura, behavioral arrest, automatism, and...
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