Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

14 results
Display

Telmisartan Inhibits TNFα-Induced Leukocyte Adhesion by Blocking ICAM-1 Expression in Astroglial Cells but Not in Endothelial Cells

Jang C, Kim J, Kwon Y, Jo SA

Telmisartan is an angiotensin-II receptor blocker and acts as a selective modulator of peroxisome proliferator-activated receptor gamma (PPARγ). Several studies have demonstrated that telmisartan ameliorates depression and memory dysfunction and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Activation of AMPK by Telmisartan Decreases Basal and PDGF-stimulated VSMC Proliferation via Inhibiting the mTOR/p70S6K Signaling Axis

Hwang YJ, Park JH, Cho DH

Background: Telmisartan, an angiotensin II type 1 receptor blocker (ARB), is widely used to treat hypertension by blocking the renin-angiotensin-aldosterone system. Although abnormal proliferation of vascular smooth muscle cells (VSMCs)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Exploring the beneficial role of telmisartan in sepsis-induced myocardial injury through inhibition of high-mobility group box 1 and glycogen synthase kinase-3β/nuclear factor-κB pathway

Jin Y, Wang H, Li J, Dang M, Zhang W, Lei Y, Zhao H

In the present experimental study, cecal ligation and puncture significantly increased the myocardial injury assessed in terms of excess release of creative kinase-MB (CK-MB), cardiac troponin I (cTnI), interleukin (IL)-6...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Long term effects after telmisartan administration for cardiovascular-renal axis disorder in cats

Han D, Jung DI

The interaction between the cardiac and renal systems is important in determining blood pressure and blood volume, both of which play a role in the vasomotor system and fluid balance....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Telmisartan Inhibits Nitric Oxide Production and Vessel Relaxation via Protein Phosphatase 2A-mediated Endothelial NO Synthase-Ser¹¹⁷⁹ Dephosphorylation

Cho DH

BACKGROUND: Apart from its blood pressure-lowering effect by blocking the renin-angiotensin-aldosterone system, telmisartan, an angiotensin II type 1 receptor blocker (ARB), exhibits various ancillary effects including cardiovascular protective effects in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Telmisartan increases hepatic glucose production via protein kinase C ζ-dependent insulin receptor substrate-1 phosphorylation in HepG2 cells and mouse liver

Cho KW, Cho DH

BACKGROUND: Dysregulation of hepatic glucose production (HGP) contributes to the development of type 2 diabetes mellitus. Telmisartan, an angiotensin II type 1 receptor blocker (ARB), has various ancillary effects in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Physiologically-based pharmacokinetic predictions of intestinal BCRP-mediated drug interactions of rosuvastatin in Koreans

Bae SH, Park WS, Han S, Park GJ, Lee J, Hong T, Jeon S, Yim DS

It was recently reported that the C(max) and AUC of rosuvastatin increases when it is coadministered with telmisartan and cyclosporine. Rosuvastatin is known to be a substrate of OATP1B1, OATP1B3,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Comparison of endothelial function improvement estimated with reactive hyperemia index between ramipril and telmisartan in hypertensive patients

Ki YJ, Seo JB, Kim HL, Lim WH, Seo HY, Lee JY, Chung WY

BACKGROUND: Endothelium has a function to regulate vascular tone by releasing mediators either vasodilating or vasoconstricting blood vessels. Endothelial dysfunction can be measured conveniently by Reactive Hyperemia Index (RHI) with...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mixed?effects analysis of increased rosuvastatin absorption by coadministered telmisartan

Park WS, Jang D, Han S, Yim DS

The Cmax and AUC of rosuvastatin increase when it is coadministered with telmisartan. The aim of this study was to explore which of the pharmacokinetic (PK) parameters of rosuvastatin are...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Serious adverse events during clinical trial for pharmacokinetic interaction between telmisartan and chlorthalidone in healthy Korean subjects: A case report

Seong SJ, Yoon YR, Lim MS

Telmisartan is an angiotensin II receptor antagonist and chlorthalidone is a thiazide-like diuretics. In this study, we report serious adverse events (SAEs) during clinical trial for pharmacokinetic interaction between telmisartan...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effects of Antihypertensive Drugs on Bone Mineral Density in Ovariectomized Mice

Kang KY, Kang Y, Kim M, Kim Y, Yi H, Kim J, Jung HR, Park SH, Kim HY, Ju JH, Hong YS

The effects of several antihypertensive drugs on bone mineral density (BMD) and micro-architectural changes in ovariectomized (OVX) mice were investigated. Eight-week-old female C57/BL6 mice were used for this study. Three...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Telmisartan Versus Carvedilol in Hypertensive Patients with Metabolic Syndrome: Effects on Blood Pressure, Arterial Stiffness, Blood Glucose, and Lipid Metabolism

Kim YS, Kim SY, Bae JH, Nah DY, Rhee MY, Lee MM, Huh HJ, Chae SL, Kim YK

  • KMID: 1750379
  • J Korean Soc Hypertens.
  • 2010 Dec;16(4):44-53.
BACKGROUND: We compared the effects of telmisartan and carvedilol on blood pressure (BP), aortic stiffness, glucose, and lipid metabolism in hypertensive patients with metabolic syndrome (MS). METHODS: A total of 26...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of Telmisartan Compared with Valsartan on Plasma Adiponectin Levels and Arterial Stiffness in Patients with Type 2 Diabetes: A Pilot Study

Park SY, Kim SG, Park J, Lee YJ, Kim HY, Seo JA, Kim NH, Choi KM, Baik SH, Choi DS

BACKGROUND: Telmisartan, used for the treatment of hypertension, has been shown to function as a partial agonist of peroxime proliferative activated receptor-nu (PPAR-nu). Theoretically, telmisartan which simultaneously blocks the angiotensin...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Clinical Study on Anti-Hypertensive Effect and Safety of Telmisartan (Micardis ) in Mild to Moderate Hypertensive Patients

Yoon YW, Lee BK, Byun KH, Choi DH, Ahn S, Ha JW, Jang Y, Chung N, Shim WH, Cho SY, Kim SS

BACKGROUND AND OBJECTIVES: Telmisartan (Micardis ), a selective type I angiotensin II receptor blocker, has recently been introduced as a new antihypertensive agent. We evaluated its anti-hypertensive effect and safety...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr