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Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc

Rajasekaran S, Soundararajan DCR, Tangavel C, K. S. SVA, Nayagam SM, Matchado MS, Muthurajan R, Shetty AP, Kanna RM, Dharmalingam K

Study Design: Profiling proteins expressed in the nucleus pulposus of fetal intervertebral disc (IVD). Purpose: To evaluate the molecular complexity of fetal IVDs not exposed to mechanical, traumatic, inflammatory, or infective...
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Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma

Rajasekaran S, Tangavel C, Soundararajan DCR, Nayagam SM, Matchado MS, Muthurajan R, Anand KSV, Rajendran S, Shetty AP, Kanna RM, Kuppamuthu D

Objective: To catalog and characterize the proteome of normal human intervertebral disc (IVD). Methods: Nine magnetic resonance imaging (MRI) normal IVDs were harvested from 9 different brain dead yet alive voluntary...
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