- Regulation Mechanism of Long Noncoding RNAs in Colon Cancer Development and Progression
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Tang X, Qiao X, Chen C, Liu Y, Zhu J, Liu J
- KMID: 2450186
- Yonsei Med J.
- 2019 Apr;60(4):319-325.
- doi: 10.3349/ymj.2019.60.4.319
Colorectal cancer (CRC) is the second most common cause of cancer-related death worldwide, and its high rates of relapse and metastasis are associated with a poor prognosis. Despite extensive research,... -
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- Mechanisms and implications in gene polymorphism mediated diverse reponses to sedatives, analgesics and muscle relaxants
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Sun Y, Zhu H, Esmaeili E, Tang X, Wu Z
- KMID: 2540998
- Korean J Anesthesiol.
- 2023 Apr;76(2):89-98.
- doi: 10.4097/kja.22654
Responses to sedatives, analgesics and muscle relaxants vary among patients under general anesthesia, which could be ascribed to the disparities of clinical characteristics and genetic factors of individuals. Accumulating researches... -
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- Clinical Biomarkers of Neurodegeneration in REM Sleep Behavior Disorder
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Zhou J, Zhang J, Lam SP, Tang X, Wing YK
- KMID: 2223615
- J Sleep Med.
- 2015 Dec;12(2):27-33.
- doi: 10.13078/jsm.15006
Rapid eye movement sleep behavior disorder (RBD) is currently considered as a prodromal stage of alphasynucleinopathies neurodegeneration. The update data suggested that over 80% patients with idiopathic RBD eventually developed... -
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- Contrast Induced Nephropathy and 2-Year Outcomes of Iso-Osmolar Compared with Low-Osmolar Contrast Media after Elective Percutaneous Coronary Intervention
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Du M, Jiang L, Tang X, Gao Z, Xu B, Yuan J
- KMID: 2512456
- Korean Circ J.
- 2021 Feb;51(2):174-181.
- doi: 10.4070/kcj.2020.0307
Background and Objectives: This study investigated the relative incidence of contrast induced nephropathy (CIN) and long-term outcomes between iso-osmolar contrast media (IOCM) and low-osmolar contrast media (LOCM) undergoing elective percutaneous... -
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- The Development of Clinical Document Standards for Semantic Interoperability in China
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Yang P, Pan F, Liu D, Xu Y, Wan Y, Tu H, Tang X, Hu J
- KMID: 2284547
- Healthc Inform Res.
- 2011 Dec;17(4):205-213.
- doi: 10.4258/hir.2011.17.4.205
OBJECTIVES: This study is aimed at developing a set of data groups (DGs) to be employed as reusable building blocks for the construction of the eight most common clinical documents... -
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- Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ
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Li H, Qiu Y, Xie M, Ouyang C, Ding X, Zhang H, Dong W, Xiong Y, Tang X
- KMID: 2537505
- Korean J Physiol Pharmacol.
- 2023 Jan;27(1):75-84.
- doi: 10.4196/kjpp.2023.27.1.75
This study aimed to observe the protective effect of momordicine I, a triterpenoid compound extracted from momordica charantia L., on isoproterenol (ISO)-induced hypertrophy in rat H9c2 cardiomyocytes and investigate its... -
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- Myotomy of Distal Esophagus Influences Proximal Esophageal Contraction and Upper Esophageal Sphincter Relaxation in Patients with Achalasia After Peroral Endoscopic Myotomy
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Ren Y, Tang X, Chen F, Deng Z, Wu J, Nei S, Jiang B, Gong W
- KMID: 2379706
- J Neurogastroenterol Motil.
- 2016 Jan;22(1):78-85.
- doi: 10.5056/jnm15098
BACKGROUND/AIMS: The motility change after peroral endoscopic myotomy (POEM) in achalasia is currently focused on lower esophageal sphincter (LES). This study aims to investigate the correlation of motility response between... -
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- Taurocholic acid promotes hepatic stellate cell activation via S1PR2/p38 MAPK/YAP signaling under cholestatic conditions
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Yang J, Tang X, Liang Z, Chen M, Sun L
- KMID: 2541436
- Clin Mol Hepatol.
- 2023 Apr;29(2):465-481.
- doi: 10.3350/cmh.2022.0327
Background/Aims: Disrupted bile acid regulation and accumulation in the liver can contribute to progressive liver damage and fibrosis. However, the effects of bile acids on the activation of hepatic stellate... -
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- Ginsenoside Rb1 Inhibits Doxorubicin-Triggered H9C2 Cell Apoptosis via Aryl Hydrocarbon Receptor
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Zhang Y, Wang Y, Ma Z, Liang Q, Tang X, Tan H, Xiao C, Gao Y
- KMID: 2375041
- Biomol Ther.
- 2017 Mar;25(2):202-212.
- doi: 10.4062/biomolther.2016.066
Doxorubicin (DOX) is a highly effective chemotherapeutic agent; however, the dose-dependent cardiotoxicity associated with DOX significantly limits its clinical application. In the present study, we investigated whether Rb1 could prevent... -
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- Real-world outcomes of niraparib treatment in patients with ovarian cancer: the first observational multicenter study in China
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Li J, Yang J, Shou H, Zhang L, Huang X, Tang X, Zheng F, Liu F, Wu X
- KMID: 2537918
- J Gynecol Oncol.
- 2022 Aug;33(S1):S11.
- doi: 10.3802/jgo.2022.33.S11
Objective The objective of this study was to present the real-world patients’ portrait, and the results of niraparib treatment in China. Methods This study included 142 patients treated with niraparib from 8 hospitals... -
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- Endoscopic Submucosal Tunnel Dissection for Upper Gastrointestinal Submucosal Tumors Originating from the Muscularis Propria Layer: A Single-Center Study
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Tang X, Ren Y, Huang S, Gao Q, Zhou J, Wei Z, Jiang B, Gong W
- KMID: 2389349
- Gut Liver.
- 2017 Sep;11(5):620-627.
- doi: 10.5009/gnl15424
BACKGROUND/AIMS: In recent years, endoscopic submucosal tunnel dissection (ESTD) has gained popularity worldwide. The aim of this study was to evaluate the safety and efficacy of ESTD in treating upper... -
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- Efficacy and Safety of Peroral Endoscopic Myotomy in Achalasia Patients with Failed Previous Intervention: A Systematic Review and Meta-analysis
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Tan S, Zhong C, Ren Y, Luo X, Xu J, Fu X, Peng Y, Tang X
- KMID: 2513690
- Gut Liver.
- 2021 Mar;15(2):153-167.
- doi: 10.5009/gnl19234
Peroral endoscopic myotomy (POEM) has emerged as a rescue treatment for recurrent or persistent achalasia after failed initial management. Therefore, we aimed to investigate the efficacy and safety of POEM... -
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- Differences in Clinical Characteristics and Surgical Outcomes of Patients with Ischemic and Hemorrhagic Pituitary Adenomas
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Liu J, Huang P, Zhang X, Chen Y, Zheng X, Shen R, Tang X, Yang H, Li S
- KMID: 2537850
- J Korean Neurosurg Soc.
- 2023 Jan;66(1):72-81.
- doi: 10.3340/jkns.2022.0071
Objective : Ischemia and hemorrhage of pituitary adenomas (PA) caused important clinical syndrome. However, the differences on clinical characteristics and surgical outcomes between these two kinds apoplexy were less reported. Methods... -
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- Tanshinone IIA Protects Endothelial Cells from Hâ‚‚Oâ‚‚-Induced Injuries via PXR Activation
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Zhu H, Chen Z, Ma Z, Tan H, Xiao C, Tang X, Zhang B, Wang Y, Gao Y
- KMID: 2395809
- Biomol Ther.
- 2017 Nov;25(6):599-608.
- doi: 10.4062/biomolther.2016.179
Tanshinone IIA (Tan IIA) is a pharmacologically active substance extracted from the rhizome of Salvia miltiorrhiza Bunge (also known as the Chinese herb Danshen), and is widely used to treat... -
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- Long Non-Coding RNA TUG1 Attenuates Insulin Resistance in Mice with Gestational Diabetes Mellitus via Regulation of the MicroRNA-328-3p/SREBP-2/ERK Axis
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Tang X, Qin Q, Xu W, Zhang X
- KMID: 2540523
- Diabetes Metab J.
- 2023 Mar;47(2):267-286.
- doi: 10.4093/dmj.2021.0216
Background: Long non-coding RNAs (lncRNAs) have been illustrated to contribute to the development of gestational diabetes mellitus (GDM). In the present study, we aimed to elucidate how lncRNA taurine upregulated... -
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- MiR-218-5p Suppresses the Killing Effect of Natural Killer Cell to Lung Adenocarcinoma by Targeting SHMT1
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Yang Q, Li J, Hu Y, Tang X, Yu L, Dong L, Chen D
- KMID: 2446954
- Yonsei Med J.
- 2019 Jun;60(6):500-508.
- doi: 10.3349/ymj.2019.60.6.500
PURPOSE: Lung adenocarcinoma (LA) is one of the major types of lung cancer. MicroRNAs (miRNAs) play an essential role in regulating responses of natural killer (NK) cells to cancer malignancy.... -
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- The Positive Association between Subclinical Hypothyroidism and Newly-Diagnosed Hypertension Is More Explicit in Female Individuals Younger than 65
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Wang X, Wang H, Yan L, Yang L, Xue Y, Yang J, Yao Y, Tang X, Tong N, Wang G, Zhang J, Wang Y, Ba J, Chen B, Du J, He L, Lai X, Li Y, Yan Z, Liao E, Liu C, Liu L, Qin G, Qin Y, Quan H, Shi B, Sun H, Ye Z, Zhang Q, Zhang L, Zhu J, Zhu M, Li Y, Teng W, Shan Z
- KMID: 2519666
- Endocrinol Metab.
- 2021 Aug;36(4):778-789.
- doi: 10.3803/EnM.2021.1101
Background: Subclinical hypothyroidism (SCH) is the most common thyroid dysfunction, and its relationship with blood pressure (BP) has been controversial. The aim of the study was to analyze the association... -
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