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A Disintegrin and Metalloprotease with Thrombospondin Motif 2 May Contribute to Cirrhosis in Humans through the Transforming Growth Factor-beta/SMAD Pathway

Dong C, Li HJ, Chang S, Liao HJ, Zhang ZP, Huang P, Tang HH

  • KMID: 2135073
  • Gut Liver.
  • 2013 Mar;7(2):213-220.
BACKGROUND/AIMS: We aimed to investigate the correlation between a disintegrin and metalloprotease with thrombospondin motif 2 (ADAMTS-2) and transforming growth factor-beta1 (TGF-beta1) in clinical human cirrhotic tissues. METHODS: The liver tissues...
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Silencing of CXCR4 Inhibits Tumor Cell Proliferation and Neural Invasion in Human Hilar Cholangiocarcinoma

Tan XY, Chang S, Liu W, Tang HH

  • KMID: 1774548
  • Gut Liver.
  • 2014 Mar;8(2):196-204.
BACKGROUND/AIMS: To evaluate the expression of CXC motif chemokine receptor 4 (CXCR4) in the tissues of patients with hilar cholangiocarcinoma (hilar-CCA) and to investigate the cell proliferation and frequency of...
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