- Contribution of Genetic and Neuroimaging Studies towards a Better Understanding of Post-Traumatic Stress Disorder
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Kim JE, Lyoo IK, Jun C, Lee YS
- KMID: 2299967
- Korean J Biol Psychiatry.
- 2010 Nov;17(4):177-193.
significant advances have been made in understanding the biological underpinnings of post-traumatic stress disorder(PTSD), particularly in the field of genetics and neuroimaging. Association studies in candidate genes related with hypothalamic-pituitary-adrenal... -
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- Aspirin-induced Bcl-2 translocation and its phosphorylation in the nucleus trigger apoptosis in breast cancer cells
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Choi BH, Chakraborty G, Baek K, Yoon HS
- KMID: 2154266
- Exp Mol Med.
- 2013 Oct;45(10):e47.
Here, we report that B-cell lymphoma 2 (Bcl-2) is a novel target molecule of aspirin in breast cancer cells. Aspirin influenced the formation of a complex by Bcl-2 and FKBP38... -
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- Molecular Cloning of Mouse FK-506 Binding Protein 12.6 Gene and Its Biological Function and Expression Patterns in the Various Models of Heart Disease
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Cho MC, Piao H, Youn TJ, Kim DW
- KMID: 2029557
- Korean Circ J.
- 2001 Jul;31(7):711-721.
- doi: 10.4070/kcj.2001.31.7.711
BACKGROUND AND OBJECTIVES: The FK-506 binding protein 12 (FKBP12) regulates intracellular Ca2+ release by stabilizing the Ca2+-induced Ca2+-release channel (ryanodine receptor) in skeletal muscle. It has been recently shown that... -
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- A FKBP5 mutation is associated with Paget's disease of bone and enhances osteoclastogenesis
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Lu B, Jiao Y, Wang Y, Dong J, Wei M, Cui B, Sun Y, Wang L, Zhang B, Chen Z, Zhao Y
- KMID: 2382698
- Exp Mol Med.
- 2017 May;49(5):e336.
- doi: 10.1038/emm.2017.64
Paget's disease of bone (PDB) is a common metabolic bone disease that is characterized by aberrant focal bone remodeling, which is caused by excessive osteoclastic bone resorption followed by disorganized... -
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