- Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease
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Lee SH, Somlo S
- KMID: 2224270
- Kidney Res Clin Pract.
- 2014 Jun;33(2):73-78.
The primary cilium of renal epithelia acts as a transducer of extracellular stimuli. Polycystin (PC)1 is the protein encoded by the PKD1 gene that is responsible for the most common... -
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- Polycystin-1 Expression in Fetal, Adult and Autosomal Dominant Polycystic Kidney
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Chae SW, Cho EY, Park MS, Lee KB, Kim H, Kim U
- KMID: 1778422
- J Korean Med Sci.
- 2006 Jun;21(3):425-429.
- doi: 10.3346/jkms.2006.21.3.425
The mutation of the PKD1 gene causes autosomal dominant polycystic kidney disease (ADPKD), and the PKD1 gene encodes polycystin-1 (PC-1). PC-1 is thought to be a cell-cell/matrix adhesion receptor molecule... -
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