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Exogenous Local Hyperthermia at 41o C Is Effective to Eliminate Mouse Model of Sporotrichosis, Independent of Neutrophil Extracellular Traps Formation

Wang YL, Qi RQ, Lan J, Li ZX, Gao XH

Background: Local hyperthermia is recommended for the treatment of patients with fixed cutaneous sporotrichosis, though the effectiveness and mechanisms of action remain elusive. While neutrophils represent the main inflammatory cells...
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Extracellular Trap by Blood Cells: Clinical Implications

Nija RJ, Sanju S, Sidharthan N, Mony U

BACKGROUND: Extracellular trap formation (ETosis) by various blood cells has been reported. This trap contains DNA, histones and granular proteins which can elicit an innate immune response by entrapping microorganisms....
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Clinical Manifestations and Computed Tomography Findings of Trapdoor Type Medial Orbital Wall Blowout Fracture

Hwang SH, Park SJ, Chi M

PURPOSE: To report the clinical manifestations and computed tomography (CT) findings of patients with a trapdoor type medial orbital wall blowout fracture. METHODS: From March 2009 to October 2016, the clinical...
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Autophagy in neutrophils

Shrestha S, Lee JM, Hong CW

Autophagy is a highly conserved intracellular degradation and energy-recycling mechanism that contributes to the maintenance of cellular homeostasis. Extensive researches over the past decades have defined the role of autophagy...
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Inhibition of Osteoclast differentiation based on precipitation time of titanium surfaces immersed in modified simulated body fluid

Chang HM, Heo SJ, Kim SK, Koak JY

PURPOSE: The purpose of this study is to investigate the changes of osteoclast differentiation inhibition according to the period of precipitation when titanium disks were immersed in Modified simulated body...
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Anti-osteoporotic and Antioxidant Activities by Rhizomes of Kaempferia parviflora Wall. ex Baker

Thao NP, Luyen BT, Lee SH, Jang HD, Kim YH

In this report, we investigated the antioxidant (peroxyl radical-scavenging and reducing capacities) and anti-osteoporotic activities of extracts and isolated constituents (1 - 16) from the rhizomes of Kaempferia parviflora Wall....
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Seasonal Abundance of Deer and Horse Flies (Diptera: Tabanidae) in the Northern Part of Gyeonggi-do, Republic of Korea

Suh SJ, Kim HC, Chong ST, Kim MS, Klein TA

The seasonal abundance of horse and deer flies (family Tabanidae) was analyzed using Mosquito Magnet(R) traps at 5 sites located near/in the demilitarized zone, northern Gyeonggi-do, Republic of Korea from...
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Phytochemical Constituents from the Aerial Part of Ducrosia ismaelis Asch

Morgan AM, Kim JH, Lee HW, Lee SH, Lim CH, Jang HD, Kim YH

Phytochemical investigation of the aerial components of Ducrosia ismaelis Asch. led to the isolation of six known compounds, psoralen (1), isopsoralen (2), cnidioside A (3), (-)-syringaresinol-O-beta-D-glucopyranoside (4), (E)-plicatin B (5),...
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Regulation of matrix metalloproteinase-9 protein expression by 1alpha,25-(OH)2D3 during osteoclast differentiation

Gu JH, Tong XS, Chen GH, Liu XZ, Bian JC, Yuan Y, Liu ZP

To investigate 1alpha,25-(OH)2D3 regulation of matrix metalloproteinase-9 (MMP-9) protein expression during osteoclast formation and differentiation, receptor activator of nuclear factor kappaB ligand (RANKL) and macrophage colony-stimulating factor (M-CSF) were administered...
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Combined blockade of HER2 and VEGF exerts greater growth inhibition of HER2-overexpressing gastric cancer xenografts than individual blockade

Singh R, Kim WJ, Kim PH, Hong HJ

  • KMID: 2154271
  • Exp Mol Med.
  • 2013 Nov;45(11):e52.
Gastric cancer overexpressing the human epidermal growth factor 2 (HER2) protein has a poor outcome, although a combination of chemotherapy and the anti-HER2 antibody trastuzumab has been approved for the...
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Neutrophils in Immunity

Woo SY

Neutrophils are the most abundant white blood cells in the peripheral blood and have long been recognized as the major phagocytes in acute infection by destroying extracellular pathogens. Although research...
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Biomarkers for identifying the early phases of osteoarthritis secondary to medial patellar luxation in dogs

Alam MR, Ji JR, Kim MS, Kim NS

The levels of tartrate resistant acid phosphatase (TRAP), matrix metalloproteinase-2 (MMP-2), and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in synovial fluid (SF) and serum in cases of canine osteoarthritis (OA)...
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A Study of Different Aspects of Blowout Fracture Between Preoperative CT and Intraoperative Images

Ham DS, Lee CH, Yang JW

PURPOSE: To analyze the morphologic differences in blowout fracture seen on preoperative CT images compared to intraoperative images. METHODS: The present study included 63 patients (63 eyes) with orbital fractures that...
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A case of acardiac twin pregnancy with fetus survival after successful radiofrequency ablation of umbilical cord

Jang JH, Moon MJ, Park HR, Ahn EH, Jung SH, Lee YM, Kim EA

Acardiac twin is a rare anomaly that occurs 1% in monochorionic twins and 1 in 35,000 pregnancies overall. Acardiac twin, also known as twin-reversed arterial perfusion (TRAP) sequence, involves a...
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Telomeric Dynamics and Telomerase Activity in Early Bovine Embryos

Jung YH, Lee SH, Cho SR, Kong IK, Cho JD, Sohn SH

  • KMID: 2070990
  • Korean J Reprod Med.
  • 2009 Jun;36(2):101-109.
OBJECTIVE: This study was carried out to analyze the amount of telomeric DNA and telomerase activity in early bovine embryos. METHODS: The amount of telomeric DNA in early bovine embryos at...
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Efficiency Evaluation of Nozawa-Style Black Light Trap for Control of Anopheline Mosquitoes

Lee HI, Seo BY, Shin EH, Burkett DA, Lee JK, Shin YH

House-residual spraying and insecticide-treated bed nets have achieved some success in controlling anthropophilic and endophagic vectors. However, these methods have relatively low efficacy in Korea because Anopheles sinensis, the primary...
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Transmembrane Adaptor Proteins Positively Regulating the Activation of Lymphocytes

Park I, Yun Y

Engagement of the immunoreceptors initiates signaling cascades resulting in lymphocyte activation and differentiation to effector cells, which are essential for the elimination of pathogens from the body. For the transduction...
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The effect of Actinobacillus actinomycetemcomitans lipopolysaccharide on rat periodontal tissues

Kim CC, Cui DZ, Kim YJ

No abstract available.
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Direct Detection of Reactive Nitrogen Species in Experimental Autoimmune Uveitis

Bae SR, Wu GS, Sevanian A, Schultz BE, Zamir E, Rao NA

PURPOSE: Demonstrate unequivocally the generation of nitric oxide in experimental autoimmune uveoretinitis by electron spin resonance spectroscopy (ESR) using ferrous iron complex of N-methyl-D-glucamine dithiocarbamate, (MGD)2-Fe2+, as a spin...
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The effects of tooth movement after corticotomy on the surrounding bone of upper molar in rats

Lee SY, Park SH, Park YH, Lee W

  • KMID: 1814537
  • J Korean Assoc Oral Maxillofac Surg.
  • 2007 Dec;33(6):684-689.
The aim of this study is to examine the change of the osteoclastic activity in the surrounding bone with or without tooth movement after corticotomy by histologic study. Eighteen male...
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