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Bcl-2 Knockdown Accelerates T Cell Receptor-Triggered Activation-Induced Cell Death in Jurkat T Cells

Lee YJ, Won TJ, Hyung KE, Lee MJ, Moon YH, Lee IH, Go BS, Hwang KW

Cell death and survival are tightly controlled through the highly coordinated activation/inhibition of diverse signal transduction pathways to insure normal development and physiology. Imbalance between cell death and survival often...
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Elevated TRAF4 expression impaired LPS-induced autophagy in mesenchymal stem cells from ankylosing spondylitis patients

Li J, Wang P, Xie Z, Yang R, Li Y, Wu X, Su H, Deng W, Wang S, Liu Z, Cen S, Ouyang Y, Wu Y, Shen H

Ankylosing spondylitis (AS) is a type of autoimmune disease that predominantly affects the spine and sacroiliac joints. However, the pathogenesis of AS remains unclear. Some evidence indicates that infection with...
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