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Risk of malignancy in patients with rheumatoid arthritis after anti-tumor necrosis factor therapy: results from Korean National Health Insurance claims data

Jung SM, Kwok SK, Ju JH, Park YB, Park SH

BACKGROUND/AIMS: Inhibition of tumor necrosis factor (TNF) is an effective treatment for rheumatoid arthritis (RA), but safety concerns about malignancy remain. The aim of this study was to evaluate cancer...
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Incidence of Active Tuberculosis within One Year after Tumor Necrosis Factor Inhibitor Treatment according to Latent Tuberculosis Infection Status in Patients with Inflammatory Bowel Disease

Kang J, Jeong DH, Han M, Yang SK, Byeon JS, Ye BD, Park SH, Hwang SW, Shim TS, Jo KW

BACKGROUND: We investigated the incidence of active tuberculosis among patients with inflammatory bowel disease (IBD) treated with tumor necrosis factor (TNF) inhibitors, with or without latent tuberculosis infection (LTBI). METHODS: The...
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Drug Survival Rates of Tumor Necrosis Factor Inhibitors in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis

Kang JH, Park DJ, Lee JW, Lee KE, Wen L, Kim TJ, Park YW, Lee SS

We investigated the compliance of Korean patients using tumor necrosis factor (TNF) inhibitors to treat rheumatoid arthritis (RA) and ankylosing spondylitis (AS), and identified potential predictors associated with treatment discontinuation....
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Prediction for TNF Inhibitor Users in RA Patients According to Reimbursement Criteria Based on DAS28

Won S, Sung YK, Cho SK, Choi CB, Koh EM, Kim SK, Kim J, Kim TH, Kim HA, Nah SS, Bang SY, Suh CH, Shim SC, Yoo DH, Yoon BY, Lee SH, Lee SW, Lee SS, Lee YA, Lee J, Lee J, Lee HS, Lim MK, Jun JB, Jeon CH, Jung YO, Chung WT, Cha HS, Choe JY, Hong SJ, Bae SC

OBJECTIVE: The purpose of this study is to examine the difference between the numbers of patients in rheumatoid arthritis (RA) who are eligible to TNF inhibitors by the past Korean...
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A Case of Rituximab Use in Rheumatoid Arthritis Following Anti-TNF-Associated Tuberculosis

Kim KH, Moon KW, Heo JW, Lee WH, Lee SH, Jeong CM, Park HS

Rituximab has been shown to be effective in rheumatoid arthritis (RA) and is recommended for patients exhibiting an inadequate response to tumor necrosis factor (TNF) inhibitors. To date, there have...
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TNF Inhibitor Use during the Perioperative Period

Ko HJ, Park SH

  • KMID: 2334861
  • J Korean Rheum Assoc.
  • 2009 Sep;16(3):175-180.
Tumor necrosis factor (TNF) inhibitors are now established as therapeutic agents for treating active rheumatoid arthritis (RA) that is resistant to conventional drug treatment. However, TNF Inhibitors decrease resistance to...
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TNF Inhibitors and Uveitis in Ankylosing Spondylitis

Kim HS, Kim TJ, Bae SC, Yoo DH, Jun JB, Kim TH

Uveitis is the most common extra-articular manifestation of ankylosing spondylitis, and this occurs in 30~50% of the patients with ankylosing spondylitis. The main symptoms of ankylosing spondylitis are usually highly...
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Use of TNF Inhibitor in Particular Clinical Settings

Lee SH

  • KMID: 2334876
  • J Korean Rheum Assoc.
  • 2009 Dec;16(4):264-270.
Tumor necrosis factor (TNF) inhibitors have been established as therapeutic agents for treating refractory systemic rheumatic diseases including rheumatoid arthritis and ankylosing spondylitis. While TNF inhibitors can effectively decrease the...
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Guidelines for Prevention of Tuberculosis in Patients with Rheumatoid Arthritis Treated with TNF-alpha Blockers

Kwok SK, Park SH

Introduction of tumor necrosis factor (TNF) inhibitor for the treatment of rheumatoid arthritis (RA) induces not only significant improvement of symptoms and signs of RA but also substantial inhibition of...
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