- Plasma Levels and Diagnostic Utility of Macrophage Colony-Stimulating Factor, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinases-1 as New Biomarkers of Breast Cancer
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Lawicki S, Glazewska , Sobolewska M, Bedkowska , Szmitkowski M
- KMID: 2373531
- Ann Lab Med.
- 2016 May;36(3):223-229.
- doi: 10.3343/alm.2016.36.3.223
BACKGROUND: Macrophage colony-stimulating factor (M-CSF), matrix metalloproteinase-9 (MMP-9), and its specific tissue inhibitor - tissue inhibitor of metalloproteinases-1 (TIMP-1) may play an important role in the pathogenesis and spread of... -
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- Prominent IL-12 Production and Tumor Reduction in Athymic Nude Mice after Toxoplasma gondii Lysate Antigen Treatment
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Pyo KH, Jung BK, Xin CF, Lee YW, Chai JY, Shin EH
- KMID: 2069810
- Korean J Parasitol.
- 2014 Dec;52(6):605-612.
- doi: 10.3347/kjp.2014.52.6.605
Toxoplasma gondii is an intracellular protozoan parasite that causes a Th1 cellular immunity. Our previous study showed that T. gondii lysate antigen (TLA) treatment in S180 tumor-bearing mice resulted in... -
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- Curcumin Induced Decreased Expression of Type I Collagen in Human Skin Fibroblast Through Down-regulation of Smad2/3 Expressions
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Ryu HW, Kim SP, Lee KS, Cho JW
- KMID: 2247498
- Korean J Dermatol.
- 2012 Jan;50(1):1-7.
BACKGROUND: Imbalance among TGF-beta/Smad pathway, MMP-1, and TIMP-1 expressions results in sclerotic skin disease, such as scleroderma, hypertrophic scar, and keloids. Curcumin, a phytochemical extracted from the rhizomes of Curcuma... -
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- The Efficacy of Shikonin on Cartilage Protection in a Mouse Model of Rheumatoid Arthritis
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Kim YO, Hong SJ, Yim SV
- KMID: 2285403
- Korean J Physiol Pharmacol.
- 2010 Aug;14(4):199-204.
- doi: 10.4196/kjpp.2010.14.4.199
The potential therapeutic action of shikonin in an experimental model of rheumatoid arthritis (RA) was investigated. As a RA animal model, DBA/1J mice were immunized two times with type II... -
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- The mRNA expression of MMP-1, TIMP-1, TGF-beta1 in gingival keratocytes from gingival hyperplasia induced by cyclosporine A
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Kang HS, Lee JS, Bing JH, Park CJ, Im JJ, Hwang KG, Shim KS
- KMID: 2190164
- J Korean Assoc Oral Maxillofac Surg.
- 2008 Aug;34(4):405-411.
PURPOSE: Cyclosporine A (CsA) is a versatile immunosuppresive agent used to prevent graft rejection syndrome and treat autoimmune disease. One of the major side effects associated with CsA is the... -
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- The Influence of Diabetes on of PGE2, MMP-14 and TIMP Expressions in Human Chronic Periodontitis
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Kim SW, Park JW, Suh JY, Lee JM
- KMID: 1999616
- J Korean Acad Periodontol.
- 2007 Dec;37(4):755-766.
- doi: 10.5051/jkape.2007.37.4.755
PURPOSE: The purposes of this study were to compare and quantify the expression of PGE2, MMP-14 and TIMP-1 in the gingival tissues of patients with type 2 diabetes mellitus and... -
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- The comparison of inflammatory mediator expression in gingival tissues from human chronic periodontitis patients with and without type 2 diabetes mellitus
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Joo SD, Lee JM
- KMID: 1511579
- J Korean Acad Periodontol.
- 2007 Aug;37(Suppl):353-369.
- doi: 10.5051/jkape.2007.37.Suppl.353
No abstract available. -
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- SP1 Mediates IFNgamma-induced TIMP-1 Transctription in C6 Astroglioma Cells
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Shin JH, Kim SW, Kim ID, Lee MH, Lee JK
- KMID: 2092892
- Korean J Anat.
- 2007 Jun;40(2):77-83.
Tissue inhibitors of metalloproteinases (TIMPs) comprise a family of secreted multifunctional proteins that consists of four members (TIMP-1 to TIMP-4). TIMPs are all major inhibitors of most matrix metalloproteinases (MMPs).... -
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- The Effects of Dehydroepiandrosterone-pyruvate on Human Osteoarthritic Chondrocytes
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Lee MC, Ji JH, Kim WY, Do JH, Kim YM
- KMID: 1575226
- J Korean Orthop Res Soc.
- 2006 Oct;9(2):153-164.
PURPOSE: To investigate the in vitro effects of Dehydroepiandrosterone (DHEA)-pyruvate on human osteoarthritic chondrocytes. METHODS: Chondrocytes isolated from human osteoarthritic knee cartilage were three-dimensionally cultured in Alginate beads. Cells were treated... -
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- The mRNA expression of growth factors in fibroblast from gingival hyperplasia induced by cyclosporine A
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Kim YM, Hwang KG, Lee JS
- KMID: 2058621
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2006 Sep;28(5):445-453.
Cyclosporine A (CsA) is a powerful immunosuppresive agent used to prevent graft rejection of organ and treat autoimmune disease. One of the major side effects associated with CsA treatment is... -
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- Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 after Administration of Endotoxin in Diabetic Rats
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Seo KH, Choi JS, Na JO, Uh ST, Kim YH, Park CS
- KMID: 1970265
- Tuberc Respir Dis.
- 2006 Sep;61(3):256-264.
- doi: 10.4046/trd.2006.61.3.256
BACKGROUND: An acute lung injury(ALI) is characterized by the recruitment, activation, and apoptosis of inflammatory cells, numerous products released by inflammatory cells such as reactive oxygen species, inflammatory mediators, and... -
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- MMP and TIMP production in periodontal ligament fibroblasts stimulated by Prevotella nigrescens lipopolysaccharide
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Yang WK, Lee W, Kim MR, Son HH
- KMID: 2416536
- J Korean Acad Conserv Dent.
- 2005 Sep;30(5):372-384.
The purpose of this study was to monitor the secretion of matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) by human periodontal ligament (PDL) fibroblasts stimulated with Prevotella nigrescens... -
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- The growth factors expression of cyclosporine induced gingival overgrowth
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Kim YJ, Hwang KG, Oh Y, Paik SS, Shim KS
- KMID: 2005032
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2005 Sep;27(5):438-445.
Cyclosporine A(CsA) is a powerful immunossuppresive agent used to prevent graft rejection of organ and treat autoimmune disease. One of the major side effects associated with CsA treatment is the... -
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- A Comparison of Expressions of MMP-3, MMP-7, TIMP-1 and Apoptosis in Keratoacanthoma and Squamous Cell Carcinoma
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Kim SY, Kim SH, Choi YW, Myung KB
- KMID: 2302644
- Korean J Dermatol.
- 2005 Apr;43(4):489-495.
BACKGROUND: Keratoacanthoma (KA) is a unique neoplasm, usually accompanied by rapid growth and regression, and the histologic findings resemble those of squamous cell carcinoma (SCC). Histologic differentiation of KA and... -
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- MMP-1 and TIMP-1 production in MG-63 cells stimulated with Prevotella nigrescens lipopolysaccharide
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Yang WK, Kim MR, Shon WJ, Lee IB, Cho BH, Um CM, Son HH
- KMID: 1987127
- J Korean Acad Conserv Dent.
- 2004 Sep;29(5):470-478.
- doi: 10.5395/JKACD.2004.29.5.470
The purpose of this study is to monitor the secretion of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) produced by human osteosarcoma cell line (MG63) stimulated with Prevotella... -
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- Alteration of airway hyperresponsiveness and expression of MMP-9 and TIMP-1 in bronchial tissue by nebulized IFN-gamma in murine model of asthma
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Lee YM, Kim YK, Park JK, Suh J, Kim KU, Kim DJ, Uh ST, Kim YH, Park CS
- KMID: 2178418
- J Asthma Allergy Clin Immunol.
- 2003 Dec;23(4):788-799.
BACKGROUND: A bronchial asthma is characterized with airway inflammation, tissue damage, and deposition of extracellular matrix protein, which may be mediated, in part, through released matrix metalloproteinase-9 (MMP-9) and tissue... -
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- Expression of CD44, MMP-2, MMP-9 and TIMP-1 in tongue squmous cell carcinoma
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Lee SH, Pyo SW, Kim YS, Choie MK
- KMID: 2118344
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2003 Jul;25(4):273-282.
Adhesion molecules and proteinases play an important role in the invasion and metastasis of a malignant tumor. However, there have not been many studies on tongue squamous cell carcinoma, the... -
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- Increased Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 Levels in the Cerebrospinal Fluid from Children with Aseptic Meningitis
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Yang JH, Park MH, Shim JY, Jung HL, Park MS, Keum DH
- KMID: 1606819
- J Korean Pediatr Soc.
- 2003 Jun;46(6):548-553.
PURPOSE: Matrix metalloproteinase(MMP)-9 is known to breakdown the blood-brain barrier by degrading the extracellular matrix of the subendothelial basement membrane in meningitis. Tissue inhibitor of metalloproteinase(TIMP)-1, a known inhibitor of... -
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- The Expressions of Matrix Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinase-1 in Scar Endometriosis and Full Term Endometrium
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Cho CH, Koh SB
- KMID: 1925514
- Korean J Obstet Gynecol.
- 2002 Aug;45(8):1311-1316.
OBJECTIVE: Endometriosis in a surgical scar following cesarian section is rare condition. And its pathogenesis has not been well established. The purpose of this study is to observe the expressions... -
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- The Relationship Between Expression of Matrix Metalloproteinases(MMPs)-2, 9 and Tissue Inhibitors of Metalloproteinase (TIMP)-1, 2 and Survival Time in Resected Non-Small Cell Lung Cancer
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Kim HR, Yang SH, Jeong ET
- KMID: 2318377
- Tuberc Respir Dis.
- 2002 May;52(5):453-462.
BACKGROUND: Matrix metalloproteinases (MMPs) are a large family of proteolytic enzymes, which are in volved in the degradation of many different components of the extracellular matrix. There is increasing evidence... -
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