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Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration

Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S

4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily, is a major costimulatory receptor that is rapidly expressed on the surface of CD4+ and CD8+ T cells after...
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Efficient amplification of melanoma-specific CD8+ T cells using artificial antigen presenting complex

Chang J

  • KMID: 1115936
  • Exp Mol Med.
  • 2006 Dec;38(6):591-598.
In vitro large amplification of tumor-specific cytotoxic T lymphocytes (CTLs) and adoptive transfer of these cells is one of the most promising approaches to treat malignant diseases in which an...
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Newly dentified members of the TNF recept or superfamily (mTNFRH1 and mTNFRH2) inhibit T-cell proliferation

Kim J, La S, Kim BS, Kwon BS, Kwon B

  • KMID: 1094695
  • Exp Mol Med.
  • 2003 Jun;35(3):154-159.
By searching an EST database, we identified two TNF receptor superfamily members (named mTNFRH1 and mTNFRH2). Amino acid sequences are highly conserved between the two receptors (78% identity). The chromosomal...
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Requirements for in vitro growth of human thymocytes

Park SH, Bae YM, Park WS, Kim TJ, Chung DH, Song HG, Cho BJ, Kim CW, Lee SK

Since it is difficult to study human thymocyte maturation in vitro, we have developed an in vitro thymocyte culture system which has allowed us to select the optimal growth conditions...
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Detection of Putative T cell Clones Using T cell Receptor beta Chain Gene Clonality Assay in Korean Patients with Aplastic Anemia

Choi HJ, Shin MG, Kim HR, Kim HJ, Kook H, Kee SJ, Kim SH, Shin JH, Suh SP, Ryang DW

BACKGROUND: We analyzed T cell receptor beta chain (TCRB) gene to investigate the presence of putative T cell clones and its clinicopathologic implications in Korean patients with aplastic anemia (AA)....
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