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The Role of CYP2B6*6 Gene Polymorphisms in 3,5,6-Trichloro-2-pyridinol Levels as a Biomarker of Chlorpyrifos Toxicity Among Indonesian Farmers

Liem JF, Suryandari DA, Malik SG, Mansyur M, Soemarko DS, Kekalih A, Subekti I, Suyatna FD, Pangaribuan B

Objectives: One of the most widely used pesticides today is chlorpyrifos (CPF). Cytochrome P450 (CYP)2B6, the most prominent catalyst in CPF bioactivation, is highly polymorphic. The objective of our study...
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Effects of α-tocopherol on hemolysis and oxidative stress markers on red blood cells in β-thalassemia major

Sovira N, Lubis M, Wahidiyat PA, Suyatna FD, Gatot D, Bardosono S, Sadikin M

Background: The accumulation of unpaired α-globin chains in patients with β-thalassemia major may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia. Multiple blood transfusions and iron overload cause cellular oxidative...
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