- Nerve growth factor upregulates sirtuin 1 expression in cholestasis: a potential therapeutic target
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Tsai MS, Lee PH, Sun CK, Chiu TC, Lin YC, Chang IW, Chen PH, Kao YH
- KMID: 2438356
- Exp Mol Med.
- 2018 Jan;50(1):e426.
- doi: 10.1038/emm.2017.235
This study investigated the regulatory role of nerve growth factor (NGF) in sirtuin 1 (SIRT1) expression in cholestatic livers. We evaluated the expression of NGF and its cognate receptors in... -
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- Infusion of Human Mesenchymal Stem Cells Improves Regenerative Niche in Thioacetamide-Injured Mouse Liver
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Kao YH, Lin YC, Lee PH, Lin CW, Chen PH, Tai TS, Chang YC, Chou MH, Chang CY, Sun CK
- KMID: 2507320
- Tissue Eng Regen Med.
- 2020 Oct;17(5):671-682.
- doi: 10.1007/s13770-020-00274-4
BACKGROUND: This study investigated whether xenotransplantation of human Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) reduces thioacetamide (TAA)-induced mouse liver fibrosis and the underlying molecular mechanism. METHODS: Recipient NOD/SCID mice were injected... -
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