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Effects of Amisulpride Adjunctive Therapy on Working Memory and Brain Metabolism in the Frontal Cortex of Patients with Schizophrenia: A Preliminary Positron Emission Tomography/Computerized Tomography Investigation

Park JH, Hong JS, Kim SM, Min KJ, Chung US, Han DH

OBJECTIVE: Dopamine plays a significant role in working memory by acting as a key neuromodulator between brain networks. Additionally, treatment of patients with schizophrenia using amisulpride, a pure dopamine class...
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The Role of Spinal Dopaminergic Transmission in the Analgesic Effect of Nefopam on Rat Inflammatory Pain

Kim DY, Chae JW, Lim CH, Heo BH, Park KS, Lee HG, Choi JI, Yoon MH, Kim WM

BACKGROUND: Nefopam has been known as an inhibitor of the reuptake of monoamines, and the noradrenergic and/or serotonergic system has been focused on as a mechanism of its analgesic action....
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Response of I(Kr) and hERG Currents to the Antipsychotics Tiapride and Sulpiride

Jo SH, Lee SY

The human ether-a-go-go-related gene (hERG) channel is important for repolarization in human myocardium and is a common target for drugs that prolong the QT interval. We studied the effects of...
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Effects of Levosulpiride in Patients with Nonspecific Esophageal Motility Disorder

Kang CD, Song CW, Lee JW, Hur BW, Jeen YT, Chun HJ, Um SH, Kim CD, Ryu HS, Hyun JH, Choe JG

  • KMID: 2305016
  • Korean J Gastrointest Motil.
  • 1999 Nov;5(2):111-118.
BACKGROUND/AIMS: Levosulpiride is the levo-enantiomer of sulpiride, a well-known antiemetic, antidyspeptic and antipsychotic drug. This study was undertaken to investigate the effects of levosulpiride on esophageal symptoms, esophageal peristalsis, and...
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Sulpiride in Meige's Syndrome: Possible Role of Glutamate

Lee SA, Kim JS, Ahn JH, Choi KG

Sulpiride, a selective antagonist for adenylate cyclase-independent dopamine receptors, was administrated to 25 patients with blepharospasm and oromandibular dystonia(Meige's syndrome). Of the 25, 7 patients (28%) exhibited marked and lasting...
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