- Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor
-
Jang JW
- KMID: 1381460
- Korean J Hepatol.
- 2008 Sep;14(3):305-308.
- doi: 10.3350/kjhep.2008.14.3.305
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Protein kinase A mediates microglial activation induced by plasminogen and gangliosides
-
Min KJ, Yang MS, Jou I, Joe EH
- KMID: 1123767
- Exp Mol Med.
- 2004 Oct;36(5):461-467.
In the injured brain, microglia is known to be activated and produce proinflammatory mediators such as interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and inducible nitric oxide synthase (iNOS). We investigated... -
- CITED
-
- Close
- SHARE
-
- Close
- Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1
-
Jung YA, Kim HK, Bae KH, Seo HY, Kim HS, Jang BK, Jung GS, Lee IK, Kim MK, Park KG
- KMID: 2155338
- Exp Mol Med.
- 2014 Jan;46(1):e73.
- doi: 10.1038/emm.2013.143
Hepatic steatosis is common in obese individuals with hyperinsulinemia and is an important hepatic manifestation of metabolic syndrome. Sterol regulatory binding protein-1c (SREBP-1c) is a master regulator of lipogenic gene... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of relaxation responses of cavernous and trigonal smooth muscles from rabbits by alpha1-adrenoceptor antagonists; prazosin, terazosin, doxazosin, and tamsulosin
-
Seo KK, Lee MY, Lim SW, Kim SC
- KMID: 1062200
- J Korean Med Sci.
- 1999 Feb;14(1):69-74.
- doi: 10.3346/jkms.1999.14.1.69
Alpha1a-adrenergic receptor (AR) primarily mediates the contraction of the prostatic and cavernous smooth muscles. Among clinically available alpha1-AR antagonists for the medical management of benign prostatic hyperplasia (BPH), tamsulosin has... -
- CITED
-
- Close
- SHARE
-
- Close
- Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells
-
Lee EJ, Choi EM, Kim SR, Park JH, Kim H, Ha KS, Kim YM, Kim SS, Choe M, Kim JI, Han JA
- KMID: 756069
- Exp Mol Med.
- 2007 Aug;39(4):469-476.
Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood. While cyclooxygeanse-2 (COX-2) is known to be closely associated with tumor growth and metastasis in... -
- CITED
-
- Close
- SHARE
-
- Close
- Protein kinase C micron plays an essential role in hypertonicity-induced heat shock protein 70 expression
-
Lim YS, Lee JS, Huang TQ, Seo JS
- KMID: 1072940
- Exp Mol Med.
- 2008 Dec;40(6):596-606.
- doi: 10.3858/emm.2008.40.6.596
Heat shock protein 70 (HSP70), which evidences important functions as a molecular chaperone and anti-apoptotic molecule, is substantially induced in cells exposed to a variety of stresses, including hypertonic stress,... -
- CITED
-
- Close
- SHARE
-
- Close
- Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes
-
Choi YA, Lee DJ, Lim HK, Jeong JH, Sonn JK, Kang SS, Baek SH
- KMID: 1097104
- Exp Mol Med.
- 2004 Jun;36(3):226-232.
IL-1beta is known promote cyclooxygenase-2 (COX- 2) and matrix metalloproteinase-2 (MMP-2) expression. This study focuses on the characterization of the signaling cascade associated with IL-1beta-induced matrix metalloproteinase-2 (MMP- 2) regulation... -
- CITED
-
- Close
- SHARE
-
- Close
