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MLH1 promoter hypermethylation predicts poorer prognosis in mismatch repair deficiency endometrial carcinomas

Kaneko E, Sato N, Sugawara T, Noto A, Takahashi K, Makino K, Terada Y

Objective The antitumor effects of anti-PD-1 antibody against mismatch repair deficiency (MMR-D)-associated cancers have been reported. MMR-D is found in approximately 20%–30% of endometrial carcinomas (ECs) and frequently occurs due to...
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Intramedullary Schwannoma of the Spinal Cord: A Nationwide Analysis by the Neurospinal Society of Japan

Hara T, Mizuno M, Hida K, Sasamori T, Miyoshi Y, Uchikado H, Ohashi H, Sugawara T, Takeshima Y, Ohara Y, Kondo A, Endo T, for the Investigators of Intramedullary Spinal Cord Tumors in the Neurospinal Society of Japan

Objective: This study was aimed to report the clinical characteristics of intramedullary schwannomas and discuss imaging findings and treatment strategies. Methods: The inclusion criterion was consecutive patients with intramedullary schwannomas who...
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