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Expression of pancreatic and duodenal homeobox1 (PDX1) protein in the interior and exterior regions of the intestine, revealed by development and analysis of Pdx1 knockout mice

Hashimoto , Kamisako T, Kagawa T, Haraguchi , Yagoto M, Takahashi , Kawai K, Suemizu H

We developed pancreatic and duodenal homeobox1 (Pdx1) knockout mice to improve a compensatory hyperinsulinemia, which was induced by hyperplasia in the beta cells or Langerhans' islands, as the diabetic model...
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Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta

Bamba Y, Nonaka M, Sasaki N, Shofuda T, Kanematsu , Suemizu H, Higuchi Y, Pooh RK, Kanemura Y, Okano H, Yamasaki M

STUDY DESIGN: We established induced pluripotent stem cells (iPSCs) and neural stem/progenitor cells (NSPCs) from three newborns with spina bifida aperta (SBa) using clinically practical methods. PURPOSE: We aimed to develop...
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