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Silymarin Inhibits Cytokine-Stimulated Pancreatic Beta Cells by Blocking the ERK1/2 Pathway

Kim EJ, Kim J, Lee MY, Sudhanva M, Devakumar , Jeon YJ

  • KMID: 2170620
  • Biomol Ther.
  • 2014 Jul;22(4):282-287.
We show that silymarin, a polyphenolic flavonoid isolated from milk thistle (Silybum marianum), inhibits cytokine mixture (CM: TNF-alpha, IFN-gamma, and IL-1beta)-induced production of nitric oxide (NO) in the pancreatic beta...
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