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Current concepts of drugs use during pregnancy

Kim YH, Cho HY

  • KMID: 1474933
  • Korean J Obstet Gynecol.
  • 2009 Aug;52(8):787-802.
More than 90% of pregnant women take drugs or use social drugs (such as tobacco and alcohol) or illicit drugs at some time during pregnancy. In general, drugs, unless absolutely...
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Cerebral Infarction Associated with Marijuana

Lee IH, Kim SM, Bae JC, Kwon KH, Lee BC

  • KMID: 2342788
  • J Korean Neurol Assoc.
  • 1999 Mar;17(2):294-297.
Whereas stroke that is associated with the use of various street drugs has been frequently noted, cerebral infarction related to marijuana has been rarely reported. We experienced a 36 year-old...
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Erectile Dysfunction Associated with Psychoactive Substances

Jiann BP

Psychoactive substances are believed to be aphrodisiac; but in reality they have deleterious effects on all the aspects of sexual function. The purpose of this article is to review and...
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Simultaneous Screening of 177 Drugs of Abuse in Urine Using Ultra-performance Liquid Chromatography with Tandem Mass Spectrometry in Drug-intoxicated Patients

Lee YW

  • KMID: 2171150
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):158-164.
OBJECTIVE: The demand for rapid and broad clinical toxicology screening methods to identify drugs of abuse and medicinal drugs is increasing steadily. Liquid chromatography-tandem mass spectrometry (LC-TMS) is increasingly used...
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Proper administration of psychostimulants

Nam B

Psychostimulants are a broad class of sympathomimetic drugs that include drugs of abuse, such as illegal substances, as well as therapeutic drugs, such as methylphenidate and modafinil. The common effect...
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Predictive Factors of Adolescents' Illicit Drug Use

Kim HY

  • KMID: 2293093
  • J Korean Acad Community Health Nurs.
  • 2007 Mar;18(1):136-145.
PURPOSE: This study was attempted to illuminate danger signals through an extensive analysis of factors influencing adolescents' illicit drug use. On this basis, it built predictive factors of adolescents' illicit...
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The Role of PKMzeta in Drug Reward Memory

Song MJ, Kim JH

  • KMID: 2287495
  • Korean J Psychopharmacol.
  • 2012 Jul;23(3):83-87.
Drug addiction is a chronic brain disease with a high incidence of relapse. Environmental cues that previously and repeatedly associated with drugs of abuse easily evoke relapse to addicts even...
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Evaluation of the Triage TOX Drug Screen Assay for Detection of 11 Drugs of Abuse and Therapeutic Drugs

Bang HI, Jang MA, Lee YW

The demand for rapid and broad clinical toxicology screens is on the rise. Recently, a new rapid toxicology screening test, the Triage TOX Drug Screen (Alere Inc., USA), which can...
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A Case of Reversible Cerebral Vasoconstriction Syndrome in a Patient Complicated with Preeclampsia

Kim SS, Moon SH, Sol YL, Kim SC, Lee DH

  • KMID: 2280867
  • Korean J Perinatol.
  • 2012 Sep;23(3):204-208.
The reversible cerebral vasoconstriction syndromes (RCVS) is a group of conditions, which is characterized by a reversible segmental constriction, typically associated with recurrent thunderclap headaches, and is often complicated by...
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Neuroimaging in Nuclear Medicine: Drug Addicted Brain

Chung YA, Kim DJ

  • KMID: 1599573
  • Nucl Med Mol Imaging.
  • 2006 Feb;40(1):1-8.
Addiction to illicit drugs is one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the...
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Medical environment and drug abuse among physicians: current state and problems in Korea

Park SS

Currently, the number of reports of propofol abuse in the general population and among physicians has increased, arousing public concerns about drug abuse. It is especially easy for physicians to...
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Amphetamine-induced ERM Proteins Phosphorylation Is through PKCbeta Activation in PC12 Cells

Jeong HJ, Kim JH, Jeon S

Amphetamine, a synthetic psychostimulant, is transported by the dopamine transporter (DAT) to the cytosol and increases the exchange of extracellular amphetamine by intracellular dopamine. Recently, we reported that the phosphorylation...
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The Role of AMPA Receptors in Synaptic Plasticity by Drugs of Abuse

Kwak MJ, Kim JH

Dopamine has long time considered as the main player in drug addiction. However, growing body of literature strongly supports a role for glutamate in addiction. 2-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors,...
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Blockade of ERK Phosphorylation in the Nucleus Accumbens Inhibits the Expression of Cocaine-induced Behavioral Sensitization in Rats

Kim S, Shin JK, Yoon HS, Kim JH

Repeated administration of psychostimulants such as cocaine leads to the development of behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in such...
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Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity

Gu SM, Kim SY, Lamichhane S, Hong JT, Yun J

Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine-induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission...
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The Effects of Prevention Programs on Drug Use in Korean Adolescents

Kim S, Kim S, Kong SS, Kim MA, Seo M

  • KMID: 2297114
  • J Korean Acad Nurs.
  • 1999 Feb;29(1):150-160.
BACKGROUND AND PURPOSE: Drug abuse is one of the most serious problems among the Korean adolescents today and has been associated with delinquent behavior in adolescents. The number of adolescents...
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Associations of the Neighborhood Environment With Substance Use: A Cross-sectional Investigation Among Patients in Compulsory Drug Detention Centers in Thailand

Yangyuen S, Kanato M, Mahaweerawat U

OBJECTIVES: To identify the associations of characteristics of the neighborhood environment with substance abuse among clients receiving treatment for drug abuse in Thailand. METHODS: A cross-sectional study was conducted of 1128...
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Transcriptional Mechanisms of Drug Addiction

Nestler EJ

Regulation of gene expression is considered a plausible mechanism of drug addiction given the stability of behavioral abnormalities that define an addicted state. Numerous transcription factors, proteins that bind to...
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Laboratory Evaluation of Cobas(R) Integra Automated Chemistry Analyzer

Lee YW, Jeong GY, Park EJ, Kim JW

  • KMID: 1892650
  • Korean J Clin Pathol.
  • 1997 Oct;17(5):735-742.
BACKGROUND: The Cobas(R) Integra is a new automated chemistry analyzer with continuous and random-access features for routine chemistries, specific proteins, electrolytes, therapeutic drugs and drugs of abuse. The system maintains...
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Annual Report on the External Quality Assessment of Therapeutic Drug Monitoring and Testing for Drugs of Abuse in Korea (2013)

Jeong TD, Gu GG, Chun S, Kim JH, Therapeutic Drug Monitoring Subcommittee, The Korean Association of Quality Assurance for Clinical Laboratory

  • KMID: 2200449
  • J Lab Med Qual Assur.
  • 2014 Mar;36(1):12-22.
We performed two trials on the external quality assessment for therapeutic drug monitoring (TDM) and testing for drugs of abuse (DOA) organized by the Therapeutic Drug Monitoring (TDM) subcommittee of...
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