- Presymptomatic Identification of CDH1 Germline Mutation in a Healthy Korean Individual with Family History of Gastric Cancer
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Choi HJ, Ki CS, Suh SP, Kim JW
- KMID: 1791955
- Ann Lab Med.
- 2014 Sep;34(5):386-389.
- doi: 10.3343/alm.2014.34.5.386
Gastric cancer (GC) is one of the most common cancers with high morbidity and mortality. Familial GC is seen in 10% of cases, and approximately 3% of familial GC cases... -
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- Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo
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Wang XT, Xie YB, Xiao Q
- KMID: 1025167
- Exp Mol Med.
- 2011 Nov;43(11):638-645.
- doi: 10.3858/emm.2011.43.11.072
The E2F-1 transcription factor is post-translationally modified and stabilized in response to various forms of DNA damage to regulate the expression of cell-cycle and pro-apoptotic genes. The sustained overexpression of... -
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- A Gene Expression in Study Human Gastric Adenocarcinoma Using a cDNA Microarray
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Lee JH, Choi SR, Hwang TH, Kim MC, Jung GJ, Roh MS, Jeong JS
- KMID: 1066039
- Korean J Gastroenterol.
- 2003 Dec;42(6):484-495.
BACKGROUND/AIMS: cDNA microarray provides a powerful alternative with an unprecedented view scope in monitoring gene expression levels and leads to discoveries of regulatory pathways involved in complicated biological processes.... -
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- Expression of c-FLIP in Gastric Cancer and its Relation to Tumor Cell Proliferation and Apoptosis
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Ryang DY, Joo YE, Chung KM, Lim SR, Jeong HK, Kim HI, Lee WS, Park CH, Kim HS, Choi SK, Rew JS, Lee JH, Park CS
- KMID: 1776678
- Korean J Intern Med.
- 2007 Dec;22(4):263-269.
- doi: 10.3904/kjim.2007.22.4.263
BACKGROUND: The expression of c-FLIP (cellular Fas-associated death domain-like interleukin-1 beta-converting enzyme (FLICE)-inhibitory protein), which is a member of the family of inhibitors of apoptosis, has been associated with... -
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- Flow cytometric DNA analysis of gastric cancer--correlation with histology and clinical outcome
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Suh KS, Min SK
- KMID: 1422002
- J Korean Med Sci.
- 1993 Oct;8(5):348-354.
- doi: 10.3346/jkms.1993.8.5.348
Nuclear DNA content was analysed by means of flow cytometric measurements in 103 patients with gastric carcinomas, using paraffin-embedded archival tissue. DNA aneuploidy was found in 40 cases (38.8%). The... -
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- p53 Codon 72 and 16-bp Duplication Polymorphisms of Gastric Cancer in Koreans
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Kim JM, Lee OY, Lee CG, Kwon SJ, Kim KS, Moon W, Koh DH, Lee HL, Yoon BC, Choi HS, Hahm JS, Lee MH, Lee DH
- KMID: 782932
- Korean J Gastroenterol.
- 2007 Nov;50(5):292-298.
BACKGROUND/AIMS: p53 gene plays an important role in cell cycle control in response to DNA damage which may increase the probability of mutations leading to carcinogenesis. The role of... -
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- Comparison of p53 gene mutations in paired primary and metastatic gastric tumor tissues
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Kim JH, Choi JJ, Noh SH, Roh JK, Min JS, Youn JK, Yoo NC, Lim HY, Carbone DP, Gazdar AF, Lee KS, Kim BS
- KMID: 1421973
- J Korean Med Sci.
- 1993 Jun;8(3):187-191.
- doi: 10.3346/jkms.1993.8.3.187
Our previous study revealed that mutations of the p53 gene were detected by cDNA sequencing in one of four (25%) primary gastric tumors and in five of six (83%) gastric... -
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