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SNP genetic polymorphisms of MDR-1, CYP1A2 and CYPB11 genes in four canine breeds upon toxicological evaluation

Gagliardi , Llambi S, Arruga MV

The fields of pharmacogenetics and pharmacogenomics have become increasingly promising regarding the clinical application of genetic data to aid in prevention of adverse reactions. Specific screening tests can predict which...
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The Role of MAPK Signaling of 1,25(OH)2D3-induced CYP24 Expression in Activated Human Macrophages

Ji JD, Lee BN, Kim TH, Woo JH, Choi SJ, Lee YH, Song GG

  • KMID: 2334913
  • J Korean Rheum Assoc.
  • 2010 Sep;17(3):254-262.
OBJECTIVE: Several important roles of 1,25(OH)2D3 have been recognized in the immune system. The availability of 1,25(OH)2D3 at the cellular level is significantly influenced by the relative abundance of enzymes...
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Prenatal diagnosis of a heterozygote of salt wasting congenital adrenal hyperplasia due to 21-hydroxylase deficiency by genetic linkage analysis

Oh BH, Park JK, Choi YM, Yang IM, Kim YS, Choi YK

For the purpose of prenatal diagnosis of CAH, genetic linkage analysis by HLA genotyping with lymphocytes and cultured amniotic cells were performed in a family at risk in which two...
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