- Effects of Mesenchymal Stem Cells Treatment on Radiation-Induced Proctitis in Rats
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Kim WH, Yoo JH, Yoo IK, Kwon CI, Hong SP
- KMID: 2539559
- Yonsei Med J.
- 2023 Mar;64(3):167-174.
- doi: 10.3349/ymj.2022.0342
Purpose: There are no effective treatment methods with which to control complications of radiation proctitis with fistula or recurrent bleeding following radiation treatment for prostate, cervical, or rectal cancer. Mesenchymal... -
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- Heterogeneity of Islet Cells during Embryogenesis and Differentiation
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Sasaki S, Miyatsuka T
- KMID: 2540514
- Diabetes Metab J.
- 2023 Mar;47(2):173-184.
- doi: 10.4093/dmj.2022.0324
Diabetes is caused by insufficient insulin secretion due to β-cell dysfunction and/or β-cell loss. Therefore, the restoration of functional β-cells by the induction of β-cell differentiation from embryonic stem (ES)... -
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- Clinical Experience of Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients Aged 60 Years and Older in South Korea
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Ji YS, Ahn JS, Yun J, Jang GH, Lim SH, Kim SH, Kim CK, Won JH, Park SK
- KMID: 2538962
- Yonsei Med J.
- 2023 Feb;64(2):123-132.
- doi: 10.3349/ymj.2022.0331
Purpose: The purpose of this study is to share our outcomes and experiences on allogeneic hematopoietic stem cell transplantation (HSCT) in elderly patients aged 60 years and older with myelodysplastic... -
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- Inhibition of Class I Histone Deacetylase Enhances Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells
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Lee Y, Lee SW, Jeong D, Lee HJ, Choi NY, Bang JS, Ham S, Ko K
- KMID: 2539618
- Int J Stem Cells.
- 2023 Feb;16(1):27-35.
- doi: 10.15283/ijsc22110
Background and Objectives: Spermatogonial stem cells (SSCs) are the most primitive cells in spermatogenesis and are the only adult stem cells capable of passing on the genome of a given... -
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- Establishing Rationale for the Clinical Development of Cell Therapy Products: Consensus between Risk and Benefit
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Han S, Yim HW, Jeong H, Choi S, Han S
- KMID: 2539617
- Int J Stem Cells.
- 2023 Feb;16(1):16-26.
- doi: 10.15283/ijsc21189
Despite long-term research achievements, the development of cell therapy (CT) products remains challenging. This is because the risks experienced by the subject and therapeutic effects in the clinical trial stage... -
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- Combinatorial Effect of Mesenchymal Stem Cells and Extracellular Vesicles in a Hydrogel on Cartilage Regeneration
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Cho WJ, Ahn J, Lee M, Choi H, Park S, Cha KY, Lee S, Arai Y, Lee SH
- KMID: 2539238
- Tissue Eng Regen Med.
- 2023 Feb;20(1):143-154.
- doi: 10.1007/s13770-022-00509-6
BACKGROUND: Mesenchymal stem cells (MSCs) are used for tissue regeneration due to their wide differentiation capacity and anti-inflammatory effects. Extracellular vesicles (EVs) derived from MSCs are also known for their... -
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- Lymphoid Lineage γδ T Cells Were Successfully Generated from Human Pluripotent Stem Cells via Hemogenic Endothelium
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Jeon SB, Han AR, Choi YB, Lee AR, Lee JY
- KMID: 2539625
- Int J Stem Cells.
- 2023 Feb;16(1):108-116.
- doi: 10.15283/ijsc22150
γδ T cells are a rare and unique prototype of T cells that share properties with natural killer cells in secondary lymphoid organs. Although many studies have revealed the function... -
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- Embryonic Stem Cells Lacking DNA Methyltransferases Differentiate into Neural Stem Cells that Are Defective in Self-Renewal
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Seo BJ, Hong TK, Yoon SH, Song JH, Uhm SJ, Song H, Hong K, Schöler HR, Do JT
- KMID: 2539620
- Int J Stem Cells.
- 2023 Feb;16(1):44-51.
- doi: 10.15283/ijsc22138
Background and Objectives: DNA methyltransferases (Dnmts) play an important role in regulating DNA methylation during early developmental processes and cellular differentiation. In this study, we aimed to investigate the role... -
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- In Vitro Generation of Luminal Vasculature in Liver Organoids: From Basic Vascular Biology to Vascularized Hepatic Organoids
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Kim HJ, Kim G, Chi KY, Kim JH
- KMID: 2539616
- Int J Stem Cells.
- 2023 Feb;16(1):1-15.
- doi: 10.15283/ijsc22154
Liver organoids have gained much attention in recent years for their potential applications to liver disease modeling and pharmacologic drug screening. Liver organoids produced In Vitro reflect some aspects of... -
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- Tracking of Stem Cells from Human Exfoliated Deciduous Teeth Labeled with Molday ION Rhodamine-B during Periodontal Bone Regeneration in Rats
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Zhang N, Xu L, Song H, Bu C, Kang J, Zhang C, Yang X, Han F
- KMID: 2539624
- Int J Stem Cells.
- 2023 Feb;16(1):93-107.
- doi: 10.15283/ijsc21204
Background and Objectives: Chronic periodontitis can lead to alveolar bone resorption and eventually tooth loss. Stem cells from exfoliated deciduous teeth (SHED) are appropriate bone regeneration seed cells. To track... -
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- Synergistic Effect of Hydrogen and 5-Aza on Myogenic Differentiation through the p38 MAPK Signaling Pathway in Adipose-Derived Mesenchymal Stem Cells
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Fei W, Pang E, Hou L, Dai J, Liu M, Wang X, Xie B, Wang J
- KMID: 2539623
- Int J Stem Cells.
- 2023 Feb;16(1):78-92.
- doi: 10.15283/ijsc21238
Background and Objectives: This study aims to clarify the systems underlying regulation and regulatory roles of hydrogen combined with 5-Aza in the myogenic differentiation of adipose mesenchymal stem cells (ADSCs). Methods... -
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- Efficacy and Safety of Human Bone Marrow-Derived Mesenchymal Stem Cells according to Injection Route and Dose in a Chronic Kidney Disease Rat Model
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Chae HK, Suh N, Jang MJ, Kim YS, Kim BH, Aum J, Shin HC, You D, Hong B, Park HK, Kim CS
- KMID: 2539622
- Int J Stem Cells.
- 2023 Feb;16(1):66-77.
- doi: 10.15283/ijsc21146
Background and Objectives: We compared the efficacy and safety of human bone marrow-derived mesenchymal stem cells (hBMSC), delivered at different doses and via different injection routes in an animal model... -
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- Current Status and Future Perspectives on Stem Cell-Based Therapies for Parkinson’s Disease
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Cha Y, Park TY, Leblanc P, Kim KS
- KMID: 2539018
- J Mov Disord.
- 2023 Jan;16(1):22-41.
- doi: 10.14802/jmd.22141
Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease, affecting 1%–2% of the population over the age of 65. As the population ages, it is anticipated... -
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- The mechanism of human neural stem cell secretomes improves neuropathic pain and locomotor function in spinal cord injury rat models: through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities
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Semita IN, Utomo DN, Suroto H, Sudiana IK, Gandi P
- KMID: 2537614
- Korean J Pain.
- 2023 Jan;36(1):72-83.
- doi: 10.3344/kjp.22279
Background: Globally, spinal cord injury (SCI) results in a big burden, including 90% suffering permanent disability, and 60%–69% experiencing neuropathic pain. The main causes are oxidative stress, inflammation, and degeneration.... -
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- Busulfan, Melphalan, and Etoposide (BuME) Showed an Equivalent Effect to Busulfan, Cyclophosphamide, and Etoposide (BuCE) as Conditioning Therapy for Autologous Stem Cell Transplantation in Patients with Relapsed or High-Risk Non-Hodgkin’s Lymphoma: A Multicenter Randomized Phase II Study bythe Consortium for Improving Survival of Lymphoma (CISL)
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Kim KH, Lee JH, Lee M, Kim HG, Do YR, Park Y, Oh SY, Shin HJ, Kim WS, Park SK, Kong JH, Park MR, Yang DH, Kwak JY, Kang HJ, Mun YC, Won JH
- KMID: 2538013
- Cancer Res Treat.
- 2023 Jan;55(1):304-313.
- doi: 10.4143/crt.2022.004
Purpose High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is the standard management for relapsed or high-risk non-Hodgkin’s lymphoma (NHL). We reported the busulfan, melphalan, and etoposide (BuME) conditioning... -
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- Naringin enhances the migration and osteogenic differentiation of human dental pulp stem cells
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Kim Y, Park HJ, Kim MK, Kim YI, Bae SK, Kim HJ, Bae MK
- KMID: 2538495
- Int J Oral Biol.
- 2022 Dec;47(4):55-62.
- doi: 10.11620/IJOB.2022.47.4.55
Bioactive flavonoids have been shown to improve the biological activity of stem cells derived from different sources in tissue regeneration. The goal of this study was to see how naringin,... -
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- The stimulatory effect of Angelica tenuissima Nakai in osteoblastic/odontoblastic differentiation of human periodontal ligament stem cells
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Park WJ, Han YH
- KMID: 2537866
- Korean J Dent Mater.
- 2022 Dec;49(4):187-198.
- doi: 10.14815/kjdm.2022.49.4.187
Angelica tenuissima Nakai (ATN) is an herbal medicine used to treat toothache, headaches, and cold symptoms. However, the therapeutic effects of ATN have not been thoroughly identified. The purpose of... -
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- A Narrative Review of Advances in Neural Precursor Cell Transplantation Therapies for Spinal Cord Injury
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Kitagawa T, Nagoshi N, Okano H, Nakamura M
- KMID: 2537358
- Neurospine.
- 2022 Dec;19(4):935-945.
- doi: 10.14245/ns.2244628.314
A spinal cord injury (SCI) is a destructive event that causes a permanent deficit in neurological function because of poor regenerative potential. Transplantation therapies have attracted attention for restoration of... -
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- Current Opinion in Molecular Pathology of Ameloblastoma: A Literature Review
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Lee D, Li S, Jung H
- KMID: 2538556
- J Korean Dent Sci.
- 2022 Dec;15(2):121-131.
- doi: 10.5856/JKDS.2022.15.2.121
Ameloblastoma is the most representative epithelial odontogenic tumor in the craniofacial region. Through several studies on Ameloblastoma that have been conducted so far, we have been able to get closer... -
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- Evaluation of the effects of photobiomodulation treatment on the neuronal development of olfactory stem cells
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Ventura RD, Bae JS, Kim EH, Yoo SH, Ryu G, Mo JH
- KMID: 2537594
- Med Lasers.
- 2022 Dec;11(4):208-218.
- doi: 10.25289/ML.22.048
Background and Objectives: The goal of this study was to assess the effects of photobiomodulation (PBM) on the neuronal differentiation of olfactory stem cells (OSCs). Materials and Methods: The OSCs were... -
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