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Effect of polyadenylic.polyuridylic acid on the proliferative responsiveness of mouse thymus and spleen cells

Lee BK, Yu YJ, Youn JK

The effects of polyadenylic.polyuridylic acid [poly(A).poly(U)] on in vitro proliferations of thymus and spleen cells from C57BL/6 mice were investigated. Mice were injected intravenously with 30 micrograms of poly(A).poly(U) or...
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Kinetin inhibits apoptosis of aging spleen cells induced by D-galactose in rats

Li M, Ouyang W, Wu X, Zheng Y, Wei Y, An L

Kinetin (Kn) is a cytokinin growth factor that exerts several anti-aging and antioxidant effects on cells and organs. To investigate the mechanism underlying apoptotic events in aging cells induced by...
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Bone Marrow T Cells are Superior to Splenic T Cells to Induce Chimeric Conversion After Non-Myeloablative Bone Marrow Transplantation

Park HS, Cho SG, Park MJ, Min SY, Chang HS, Kim HJ, Lee S, Min CK, Lee JW, Min WS, Kim CC, Kim HY

BACKGROUND/AIMS: The bone marrow functions not only as the primary B-lymphocyte-producing organ but also as a secondary lymphoid organ for CD4 and CD8 cell responses and a site of preferential...
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Nickel induces secretion of IFN-gamma by splenic natural killer cells

Kim JY, Huh K, Lee KY, Yang JM, Kim TJ

Although nickel hypersensitivity is known as a delayed-type hypersensitivity mediated by nickel-specific T cells, it is greatly influenced by other immune cells. Here we show that splenic natural killer cells...
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