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Failure of topical DMSO to improve blood flow or evoked potentials in rat spinal cord injury

Park YK, Tator CH

Dimethyl sulfoxide (DMSO) is a well-known hydroxyl radical scavenger, which is readily absorbed through biological membranes. We studied the effects of locally applied DMSO on acute spinal cord injury....
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Neural toxicity induced by accidental intrathecal vincristine administration

Kwack EK, Kim DJ, Park TI, Cho KR, Kwon IH, Sohn YK

Described here is a case of accidental intrathecal administration of vincristine with pathologic findings in the central nervous system. A 3-year-old boy with acute lymphoblastic leukemia, was given his ninth...
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Effects of Corticosteroid and Electroacupuncture on Experimental Spinal Cord Injury in Dogs

Yang JW, Jeong SM, Seo KM, Nam TC

  • KMID: 1099828
  • J Vet Sci.
  • 2003 Apr;4(1):97-101.
The aim of this study is to investigate the effects of electroacupuncture, corticosteroid, and combination of two treatments on ambulatory paresis due to spinal cord injury in dogs by comparing...
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The Effect of Strychnine on Membrane Properties of Spinal Motoneurons in the Cat

Lee KC, Klee MR, Lee HJ

Strychnine (Stry.) has been used, as an instrument for studies of experimental epilepsy, though its precise mode of action has remained obscure. One mechanism of action was partially clarified in...
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Effects of DA-9701, a Novel Prokinetic Agent, on Phosphorylated Extracellular Signal-Regulated Kinase Expression in the Dorsal Root Ganglion and Spinal Cord Induced by Colorectal Distension in Rats

Lee SP, Lee KN, Lee OY, Lee HL, Jun DW, Yoon BC, Choi HS, Hwang SJ, Lee SE

  • KMID: 1774540
  • Gut Liver.
  • 2014 Mar;8(2):140-147.
BACKGROUND/AIMS: DA-9701, a standardized extract of Pharbitis Semen and Corydalis Tuber, is a new prokinetic agent that exhibits an analgesic effect on the abdomen. We investigated whether DA-9701 affects visceral...
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Inoculation of Lewis lung carcinoma cells enhances formalin-induced pain behavior and spinal Fos expression in mice

Choi JG, Kim JM, Kang DW, Choi JW, Park JB, Ahn SH, Ryu Y, Kim HW

The incidence of lung cancer has rapidly increased and cancer patients at a later cancer stage frequently suffer from unbearable cancer-associated pain. However, the pathophysiology of lung cancer pain has...
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Effects of iontophoretically applied substance P, calcitonin gene-related peptide on excitability of dorsal horn neurones in rats

Leem JW, Gwak YS, Lee EH, Chung SS, Kim YS, Nam TS

Spontaneous pain, allodynia and hyperalgesia are well known phenomena following peripheral nerve or tissue injury, and it is speculated that secondary hyperalgesia and allodynia, are generally thought...
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Spinal Gabapentin and Antinociception: Mechanisms of Action

Yoon MH, Choi JI, Jeong SW

Spinal gabapentin has been known to show the antinociceptive effect. Although several assumptions have been suggested, mechanisms of action of gabapentin have not been clearly established. The present study was...
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