- HDAC3 Inhibition Promotes Alternative Activation of Macrophages but Does Not Affect Functional Recovery after Spinal Cord Injury
-
Sanchez S, Lemmens S, Baeten P, Sommer D, Dooley D, Hendrix S, Gou Fabregas M
- KMID: 2424737
- Exp Neurobiol.
- 2018 Oct;27(5):437-452.
- doi: 10.5607/en.2018.27.5.437
After spinal cord injury (SCI), monocyte derived macrophages play a detrimental role. Histone deacetylases (HDACs) are central epigenetic regulators of macrophage-polarization. We hypothesized that HDAC3 inhibition suppresses the pro-inflammatory macrophage... -
- CITED
-
- Close
- SHARE
-
- Close
