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TcellInflamedDetector: an R package to distinguish T cell inflamed tumor types from non–T cell inflamed tumor types

Yang SD, Park HS

A major issue in the use of immune checkpoint inhibitors is their lack of efficacy in many patients. Previous studies have reported that the T cell inflamed signature can help...
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Tumor Margin Infiltration in Soft Tissue Sarcomas: Prediction Using 3T MRI Texture Analysis

Kim M, Jee WH, Lee Y, Hong, JH, Jung CK, Chung YG, Lee SY

Purpose To determine the value of 3 Tesla (T) MRI texture analysis for predicting tumor margin infiltration in soft tissue sarcomas. Materials and Methods Thirty-one patients who underwent 3T MRI and...
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A Prospective Comparative Study of Mobile Acoustic Uroflowmetry and Conventional Uroflowmetry

Lee DG, Gerber J, Bhatia V, Janzen N, Austin PF, Koh CJ, Song SH

Purpose: The aim of this study was to assess the performance of a mobile acoustic Uroflowmetry (UFM) application compared with standard UFM in the pediatric population. Methods: A mobile acoustic UFM...
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Transparency considerations for describing statistical analyses in research

Kwak SK, Kim J

Background: Researchers who use the results of statistical analyses to draw conclusions about collected data must write a statistical analysis section in their manuscript. Describing statistical analyses in precise detail...
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Expert Opinions and Recommendations for the Clinical Use of Quantitative Analysis Software for MRI-Based Brain Volumetry

Lee JY, Park JE, Chung MS, Oh SW, Moon WJ, Aging and Neurodegeneration Imaging (ANDI) Study Group, Korean Society of Neuroradiology (KSNR)

The objective assessment of atrophy and the measurement of brain volume is important in the early diagnosis of dementia and neurodegenerative diseases. Recently, several MR-based volumetry software have been developed....
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Mammography with a fully automated breast volumetric software as a novel method for estimating the preoperative breast volume prior to mastectomy

Kim JS, Bae K, Lee EJ, Bang M

Purpose: Increasing interest in maintaining a positive body image following breast cancer surgery has become an important aspect of reconstruction surgery. Volume matching of the reconstructed breast to natural breasts...
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Manufacture of the Animations on Health Information

Chung MS, Ha HM

The first author as a medical doctor has elaborated four-frame comic strips on health information. The comic strips can be easily converted into the animations by means of PowerPoint (animation...
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Computerized Sunnybrook facial grading scale (SBface) application for facial paralysis evaluation

Jirawatnotai S, Jomkoh P, Voravitvet TY, Tirakotai W, Somboonsap N

Background The Sunnybrook facial grading scale is a comprehensive scale for the evaluation of facial paralysis patients. Its results greatly depend on subjective input. This study aimed to develop and...
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Reliability of 2 Smartphone Applications for Cobb Angle Measurement in Scoliosis

Ketenci , Yanık HS, Erdoğan , Adıyeke L, Erdem

Background: As mobile technology has evolved, smartphone applications have been used for radiographic angle measurements in daily clinical practice. This study aimed to assess the reliability of 2 smartphone applications...
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Key Principles of Clinical Validation, Device Approval, and Insurance Coverage Decisions of Artificial Intelligence

Park SH, Choi J, Byeon JS

Artificial intelligence (AI) will likely affect various fields of medicine. This article aims to explain the fundamental principles of clinical validation, device approval, and insurance coverage decisions of AI algorithms...
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Optimal microcatheter shaping method customized for a patient-specific vessel using a three-dimensional printer

Kim TG

Objective: In coil embolization of cerebral aneurysms, it is very important to guide microcatheters to the appropriate location in the aneurysm and stabilize them during procedures. To do this, microcatheters...
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Clinically Available Software for Automatic Brain Volumetry: Comparisons of Volume Measurements and Validation of Intermethod Reliability

Lee JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Objective: To compare two clinically available MR volumetry software, NeuroQuant® (NQ) and Inbrain® (IB), and examine the inter-method reliabilities and differences between them. Materials and Methods: This study included 172 subjects...
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Association between Texture Analysis Parameters and Molecular Biologic KRAS Mutation in Non-Mucinous Rectal Cancer

Jo SJ, Kim SH, Park SJ, Lee Y, Son JH

Purpose To evaluate the association between magnetic resonance imaging (MRI)-based texture parameters and Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation in patients with non-mucinous rectal cancer. Materials and Methods Seventy-nine...
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Texture Analysis of Gray-Scale Ultrasound Images for Staging of Hepatic Fibrosis

Park EJ, Kim SH, Park SJ, Baek TW

Purpose: To evaluate the feasibility of texture analysis of gray-scale ultrasound (US) images for staging of hepatic fibrosis. Materials and Methods: Altogether, 167 patients who had undergone routine US and laboratory...
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Sample size determination and power analysis using the G*Power software

Kang H

Appropriate sample size calculation and power analysis have become major issues in research and publication processes. However, the complexity and difficulty of calculating sample size and power require broad statistical...
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Application of digital software as a medical devices in dental clinic

Woo K, Baik S, Kim ST

By facing the era of the 4th industrial revolution, personalized medical services for patients are expanding with the development of information and communications technology. With these changes, digital medical devices...
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Key principles of clinical validation, device approval, and insurance coverage decisions of artificial intelligence

Park SH, Choi J, Byeon JS

Artificial intelligence (AI) will likely affect various fields of medicine. This article aims to explain the fundamental principles of clinical validation, device approval, and insurance coverage decisions of AI algorithms...
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Accuracy and clinical feasibility of 3D‑myocardial thickness map measured by cardiac computed tomogram

Kwon O, Lee J, Lim S, Park J, Han H, Yang S, Hwang I, Yu H, Kim T, Uhm J, Joung B, Lee M, Pak H

Background: Although myocardial thickness is an important variable for therapeutic catheter ablation of cardiac arrhythmias, quantification of wall thickness has been overlooked. We developed a software (AMBER) that measures 3D-myocardial...
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Validation of “sasLM,” an R package for linear models with type III sum of squares

Sunwoo J, Kim H, Choi D, Bae KS

The general linear model (GLM) describes the dependent variable as a linear combination of independent variables and an error term. The GLM procedure of SAS® and the “car” package in...
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Dawn of the Visible Monkey: Segmentation of the Rhesus Monkey for 2D and 3D Applications

Kim CY, Lee AK, Choi HD, Park JS

Background: To properly utilize the sectioned images in a Visible Monkey dataset, it is essential to segment the images into distinct structures. This segmentation allows the sectioned images to be...
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