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Effect of two- or four-hour oral intake restriction on intraoperative intravascular volume optimization using stroke volume variation analysis: a single-blinded randomized controlled trial

Hoshika M, Fujita Y, Yoshizawa , Harima M, Sobue K

No abstract available.
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Age-related requisite concentration of sevoflurane for adequate sedation with combined epidural-general anesthesia

Fujita Y, Kondo A, Yamauchi H, Kako E, Sobue K

BACKGROUND: The requisite anesthetic concentration of sevoflurane required to obtain adequate sedation when sufficient analgesics are supplied has not been determined. The purpose of this study was to determine the...
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Relationship between dexmedetomidine dose and plasma dexmedetomidine concentration in critically ill infants: a prospective observational cohort study

Fujita Y, Inoue K, Sakamoto T, Yoshizawa , Tomita M, Toyo'oka T, Sobue K

BACKGROUND: Dexmedetomidine is a highly selective central α₂-agonist used as a sedative in pediatric intensive care unit (PICU). However, little is known about the relationship between dexmedetomidine dose and its...
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