- SIRT1 promotes DNA repair activity and deacetylation of Ku70
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Jeong J, Juhn K, Lee H, Kim SH, Min BH, Lee KM, Cho MH, Park GH, Lee KH
- KMID: 1103676
- Exp Mol Med.
- 2007 Feb;39(1):8-13.
Human SIRT1 controls various physiological responses including cell fate, stress, and aging, through deacetylation of its specific substrate protein. In processing DNA damage signaling, SIRT1 attenuates a cellular apoptotic response... -
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