- Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis
-
Hahm ER, Kim SH, Mathan SV, Singh RP, Singh SV
- KMID: 2517364
- J Cancer Prev.
- 2021 Jun;26(2):128-136.
- doi: 10.15430/JCP.2021.26.2.128
Diallyl trisulfide (DATS), a metabolic by-product of processed garlic, is highly effective in inhibiting growth of human breast cancer cells in vitro and in vivo, but the underlying mechanisms are... -
- CITED
-
- Close
- SHARE
-
- Close
- Breast Cancer Selective Disruption of Actin Cytoskeleton by Diallyl Trisulfide
-
Hahm ER, Mathan SV, Singh RP, Singh SV
- KMID: 2531044
- J Cancer Prev.
- 2022 Jun;27(2):101-111.
- doi: 10.15430/JCP.2022.27.2.101
Diallyl trisulfide (DATS) is an attractive anti-cancer phytochemical with in vitro and in vivo growth inhibitory effects against different solid tumors including breast cancer. We have shown previously that an... -
- CITED
-
- Close
- SHARE
-
- Close
- Diallyl Trisulfide Inhibits Leptin-induced OncogenicSignaling in Human Breast Cancer Cells but Fails toPrevent Chemically-induced Luminal-type Cancer in Rats
-
Kim SH, Hahm ER, Singh KB, Singh SV
- KMID: 2505221
- J Cancer Prev.
- 2020 Mar;25(1):1-12.
- doi: 10.15430/JCP.2020.25.1.1
Previous studies have demonstrated inhibitory effect of garlic component diallyl trisulfide (DATS) on growth of breast cancer cellsin vitro and in vivo. This study investigated the effect of DATS on... -
- CITED
-
- Close
- SHARE
-
- Close
- Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats
-
Hahm ER, Singh SV
- KMID: 2528086
- J Cancer Prev.
- 2022 Mar;27(1):22-30.
- doi: 10.15430/JCP.2022.27.1.22
Diallyl trisulfide (DATS) was shown to be a potent inhibitor of luminal-type MCF-7 xenograft growth in vivo. The present study was conducted to determine the preventive effect of DATS administration... -
- CITED
-
- Close
- SHARE
-
- Close
- Cyclooxygenase 2 gene polymorphisms and chronic periodontitis in a North Indian population: a pilot study
-
Daing A, Singh SV, Saimbi CS, Khan MA, Rath SK
- KMID: 2212074
- J Periodontal Implant Sci.
- 2012 Oct;42(5):151-157.
- doi: 10.5051/jpis.2012.42.5.151
PURPOSE: Cyclooxygenase (COX) enzyme catalyzes the production of prostaglandins, which are important mediators of tissue destruction in periodontitis. Single nucleotide polymorphisms of COX2 enzyme have been associated with increasing susceptibility... -
- CITED
-
- Close
- SHARE
-
- Close
- Prevention of Prostate Cancer in Transgenic Adenocarcinoma of the Mouse Prostate Mice by Yellow Passion Fruit Extract and Antiproliferative Effects of Its Bioactive Compound Piceatannol
-
Kido LA, Hahm ER, Kim SH, Baseggio AM, Cagnon VHA, Singh SV, Maróstica Jr. MR
- KMID: 2503565
- J Cancer Prev.
- 2020 Jun;25(2):87-99.
- doi: 10.15430/JCP.2020.25.2.87
Piceatannol (PIC), a polyphenol presents in many vegetables and fruits including yellow passion fruit extract (PFE; Passiflora edulis), has anti-cancer activity, but its molecular targets are still poorly understood. The... -
- CITED
-
- Close
- SHARE
-
- Close
