- Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway
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Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY
- KMID: 1093610
- Exp Mol Med.
- 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)... -
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- Transduction of Tat-Superoxide Dismutase into Insulin-producing MIN6N Cells Reduces Streptozotocin-induced Cytotoxicity
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Choung IS, Eum WS, Li MZ, Sin GS, Kang JH, Park J, Choi SY, Kwon HY
- KMID: 2071591
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):163-168.
The reactive oxygen species (ROS) are considered to be an important mediator in pancreatic beta cell destruction, thereby triggering the development of insulin-dependent diabetes mellitus. In the present study, HIV-1... -
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