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Selectively Decreased Expression of Peroxiredoxins Induced by Silica in Pulmonary Epithelial Cells

Lee HL, Kim YS, Park JH, Chung WY, Lee KS, Oh YJ, Sheen SS, Park KJ, Hwang SC

BACKGROUND/AIMS: Peroxiredoxin (Prx) belongs to a ubiquitous family of antioxidant enzymes that regulates many cellular processes through intracellular oxidative signal transduction pathways. Silica-induced lung damage involves reactive oxygen species (ROS)...
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