- New Insights into the Mechanism of the Down-Regulation of Mast Cells in the Treatment of Interstitial Cystitis: Possible Role of Siglecs
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Lee T
- KMID: 2232794
- Int Neurourol J.
- 2011 Jun;15(2):59-60.
No abstract available. -
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- Potential Targeting of Siglecs, Mast Cell Inhibitory Receptors, in Interstitial Cystitis
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Park CS, Bochner BS
- KMID: 2232795
- Int Neurourol J.
- 2011 Jun;15(2):61-63.
Mast cell increases and activation are detected in the chronic inflammatory bladder disease interstitial cystitis (IC), and their proinflammatory mediators are felt to contribute to regional pelvic pain and inflammatory... -
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- Functions of Siglecs in Allergic Inflammation
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Lee HH
- KMID: 2051628
- Pediatr Allergy Respir Dis.
- 2006 Sep;16(3):197-205.
Siglecs are sialic acid binding Ig-like lectins, subset of the immunoglobulin superfamily. They are characterized by a homologous N-terminal V-set Ig-like domain and C2 set Ig-like domains. N-terminal domains... -
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- Effect of Anti-Siglec-F Antibody and Reactive Oxygen Species Blocking on Histamine Release in Urinary Bladder of Ovalbumin-Treated Mice
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Choi BH, Choo GY, Kang JH, Lee CY, Park CS
- KMID: 2232963
- Int Neurourol J.
- 2012 Sep;16(3):122-125.
PURPOSE: Sialic acid-binding Ig-like lectin (Siglec) is an immune inhibitory receptor that plays a role in the negative regulation of the activation of immune cells. This study aimed to evaluate... -
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- Siglec-8: Novel Therapeutic Approach for Eosinophilic Inflammation and Airway Remodeling
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Song DJ
- KMID: 2314874
- Pediatr Allergy Respir Dis.
- 2008 Jun;18(2):114-120.
Eosinophil is an important therapeutic target in the management of asthma due to their important role in airway inflammation, induction of airway hyperresponsiveness and their recently described role in airway... -
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