- Cinnamic acid derivatives as potential matrix metalloproteinase-9 inhibitors: molecular docking and dynamics simulations
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Malekipour MH, Shirani F, Moradi S, Taherkhani A
- KMID: 2543688
- Genomics Inform.
- 2023 Mar;21(1):e9.
- doi: 10.5808/gi.22077
Matrix metalloproteinase-9 (MMP-9) is a zinc and calcium-dependent proteolytic enzyme involved in extracellular matrix degradation. Overexpression of MMP-9 has been confirmed in several disorders, including cancers, Alzheimer′s disease, autoimmune diseases,... -
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- Neuroprotective effects of chloroquine on neurological scores, blood-brain barrier permeability, and brain edema after traumatic brain injury in male rats
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Karimi M, Nazari S, Shirani F, Alivirdiloo V, Siahposht-Khachaki A, Edalatkhah S, Khanian R
- KMID: 2543388
- J Neurocrit Care.
- 2023 Jun;16(1):18-27.
- doi: 10.18700/jnc.220052
Background: Traumatic brain injury (TBI) is one of leading causes of death among young people worldwide. Chloroquine, an antimalarial drug, has been shown to easily cross the blood-brain barrier (BBB)... -
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