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Effects of developmental iron deficiency and post-weaning iron repletion on the levels of iron transporter proteins in rats

Oh S, Shin PK, Chung J

BACKGROUND/OBJECTIVES: Iron deficiency in early life is associated with developmental problems, which may persist until later in life. The question of whether iron repletion after developmental iron deficiency could restore...
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Iron Supplementation Reverses the Reduction of Hydroxymethylcytosine in Hepatic DNA Associated With Chronic Alcohol Consumption in Rats

Tammen SA, Park JE, Shin PK, Friso S, Chung J, Choi SW

BACKGROUND: Alcohol is known to affect two epigenetic phenomena, DNA methylation and DNA hydroxymethylation, and iron is a cofactor of ten-eleven translocation (TET) enzymes that catalyze the conversion from methylcytosine...
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Traditional Korean diet can alter the urine organic acid profile, which may reflect the metabolic influence of the diet

Shin PK, Chun S, Kim MS, Park SJ, Kim MJ, Kwon DY, Kim K, Lee HJ, Choi SW

Purpose: To determine the metabolic influence of the traditional Korean diet (K-diet), which has been regarded as a healthy diet, we investigated the profile of urine organic acids that are...
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Walnut phenolic extracts reduce telomere length and telomerase activity in a colon cancer stem cell model

Shin PK, Zoh Y, Choi J, Kim MS, Kim Y, Choi SW

BACKGROUND/OBJECTIVES: Telomeres are located at the chromosomal ends and progressively shortened during each cell cycle. Telomerase, which is regulated by hTERT and c-MYC, maintains telomeric DNA sequences. Especially, telomerase is...
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