- Evaluation of an Integrin αvβ3 Radiotracer, [18F]F‑FPP‑RGD2 , for Monitoring Pharmacological Effects of Integrin αv siRNA in the NASH Liver
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Hiroyama S, Matsunaga K, Ito M, Iimori H, Morita I, Nakamura J, Shimosegawa E, Abe K
- KMID: 2545313
- Nucl Med Mol Imaging.
- 2023 Aug;57(4):172-179.
- doi: 10.1007/s13139-023-00791-9
Purpose Integrin αv is a key regulator in the pathophysiology of hepatic fibrosis. In this study, we evaluated the potential utility of an integrin αvβ3 positron emission tomography (PET) radiotracer, 18F-labeled... -
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- Improved Stability and Practicality for Synthesis of 4-Borono-2-[ 18F] fluoro-L-phenylalanine by Combination of [ 18 O]O 2 Single-Use and [ 18 F]CH 3 COOF Labeling Agents
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Naka S, Watanabe T, Kanai Y, Watabe T, Tatsumi M, Kato H, Shimosegawa E, Hatazawa J
- KMID: 2528459
- Nucl Med Mol Imaging.
- 2022 Apr;56(2):86-95.
- doi: 10.1007/s13139-021-00719-1
Purpose 4-Borono-2-[ 18 F]fluoro-L-phenylalanine ([ 18 F]FBPA) synthesized with [ 18 F]F2 , produced using the 18 O(p, n) 18 F reaction, has been reported for increasing radioactivity. However, a... -
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