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Characterization of anti-factor VIII antibody in a patient with acquired hemophilia A

Oh J, Lim Y, Jang MJ, Huh JY, Shima M, Oh D

Acquired hemophilia A (AHA) is a bleeding disorder caused by the development of an auto-antibody against endogenous factor VIII (FVIII). In this study, the epitope of the autoantibody was identified...
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Interleukin-10 and interleukin-5 balance in patients with active asthma, those in remission, and healthy controls

Tomiita M, Campos-Alberto E, Shima M, Namiki M, Sugimoto K, Kojima H, Watanabe H, Sekine K, Nishimuta , Kohno Y, Shimojo N

BACKGROUND: The immunological mechanisms of asthma remission remain unclear although several reports have suggested that balance between T helper (Th) 2 cytokines and regulatory cytokines is related. OBJECTIVE: To study the...
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Prevalence of Irritable Bowel Syndrome–like Symptoms in Japanese Patients with Inactive Inflammatory Bowel Disease

Tomita T, Kato Y, Takimoto M, Yamasaki T, Kondo T, Kono T, Tozawa K, Yokoyama Y, Ikehara H, Ohda Y, Oshima T, Fukui H, Tanaka S, Shima M, Watari J, Miwa H

  • KMID: 2433459
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):661-669.
  • doi: 10.5056/jnm15160
BACKGROUND/AIMS: Few studies are available that have investigated the risk factors for overlapping irritable bowel syndrome (IBS)-like symptoms in patients with inactive inflammatory bowel disease (IBD). The present study has...
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